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鉴定和分析一种新型猫杯状病毒,该病毒属于 Hunnivirus 属。

Identification and genome characterization of a novel feline picornavirus proposed in the Hunnivirus genus.

机构信息

College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong Province, People's Republic of China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, Guangdong Province, People's Republic of China; Guangdong Technological Engineering Research Center for Pet, Guangzhou 510642, Guangdong Province, People's Republic of China.

Guangzhou Zoo, Guangzhou 510070, Guangdong Province, People's Republic of China.

出版信息

Infect Genet Evol. 2019 Jul;71:47-50. doi: 10.1016/j.meegid.2019.03.011. Epub 2019 Mar 19.

Abstract

The genus Hunnivirus, which has been identified in sheep, cattle, and rats, was first proposed in the family Picornaviridae by the International Committee on Taxonomy of Viruses in 2013. In this study, a hunnivirus was detected in fecal samples collected from a diarrheic cat in Southern China in 2017. Genome sequencing and analysis indicated that the novel hunnivirus has the same genome organization as reported for other hunniviruses, 5'UTR-L-P1(VP4-VP2-VP3-VP1)-P2(2A-2B-2C)-P3(3A-3B-3C-3D)-3'UTR, but is genetically divergent. This hunnivirus is proposed as a novel genotype of the species Hunnivirus A and provisionally designated feline hunnivirus. Our study expands the host range of hunnivirus and enriches knowledge on picornaviruses.

摘要

2013 年,国际病毒分类委员会在正呼肠孤病毒科提议将一种已在绵羊、牛和大鼠中鉴定出的 Hunnivirus 属归入其中。本研究在 2017 年从中国南方一只腹泻猫的粪便样本中检测到了一种 Hunnivirus。基因组测序和分析表明,该新型 Hunnivirus 的基因组组织与已报道的其他 Hunniviruses 相同,为 5'UTR-L-P1(VP4-VP2-VP3-VP1)-P2(2A-2B-2C)-P3(3A-3B-3C-3D)-3'UTR,但遗传上存在差异。该 Hunnivirus 被提议为 Hunnivirus A 的一个新型基因型,并暂命名为猫源 Hunnivirus。本研究扩展了 Hunnivirus 的宿主范围,丰富了小 RNA 病毒的知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb86/7106175/ded3f1797105/gr1_lrg.jpg

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