Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. I. Taxonomy, production, isolation and preliminary characterization.
作者信息
Umezawa H, Aoyagi T, Nishikiori T, Okuyama A, Yamagishi Y, Hamada M, Takeuchi T
出版信息
J Antibiot (Tokyo). 1986 Jun;39(6):737-44. doi: 10.7164/antibiotics.39.737.
PMID:3089997
Abstract
Plipastatins have been isolated as part of a program designed to find inhibitors of porcine pancreatic phospholipase A2. They were purified from fermentation broth of Bacillus cereus BMG302-fF67 and finally separated into four fractions by reverse phase HPLC. The respective fractions were designated as plipastatins A1, A2, B1 and B2. Plipastatins also inhibited phospholipases C and D.
摘要
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