黎巴嫩学龄儿童饮食与哮喘的关系：一项横断面研究。

Diet and asthma in Lebanese schoolchildren: A cross-sectional study.

机构信息

School of Pharmacy, Lebanese International University, Beirut, Lebanon.

Life Sciences and Health Department, Paris-Est University, Paris, France.

出版信息

Pediatr Pulmonol. 2019 Jun;54(6):688-697. doi: 10.1002/ppul.24280. Epub 2019 Mar 28.

DOI:10.1002/ppul.24280

PMID:30920185

Abstract

OBJECTIVES

The causes of the global increase in asthma in children are unknown. It has been hypothesized that diet is an important factor that may play a role in the pathogenesis of the disease. The objective was to evaluate the association between diet and current asthma among Lebanese children.

METHODS

A cross-sectional study was conducted on 1000 children recruited from public and private schools in Lebanon. Of the total enrolled participants, 107 children were diagnosed with current asthma and were analyzed. The food frequency questionnaire was used to assess participants' dietary habits.

RESULTS

The consumption of sweets ≥3 times weekly (ORa = 5.42), white bread ≥3 times weekly (ORa = 26.38), and olive oil daily (ORa = 9.80) were associated with higher odds of current asthma. Drinking carbonated beverages occasionally (ORa = 0.25) and ≥3 times per week (ORa = 0.03) was significantly associated with lower odds of current asthma. Adhering to Mediterranean diet (occasional, >3 times weekly and daily) was significantly associated with lower odds of current asthma compared to never consuming Mediterranean diet (ORa = 0.23 and ORa = 0.22, respectively). The occasional consumption of bread was significantly associated with higher odds of current asthma (ORa = 8.2), whereas daily consumption was significantly associated with lower odds (ORa = 0.336). Moreover, the occasional, ≥3 times weekly and daily consumption of meat were significantly associated with higher odds of current asthma (ORa = 9.6; ORa = 5.1 and ORa = 4.5), respectively. An occasional consumption of junk food was significantly associated with lower odds of current asthma (ORa = 0.044), whereas a daily consumption was associated with higher odds.

CONCLUSION

Adhering to certain diets might be associated with higher odds of current asthma.

摘要

目的

儿童哮喘全球发病率增加的原因尚不清楚。有研究假设饮食是一个重要的因素，可能在疾病的发病机制中起作用。本研究旨在评估黎巴嫩儿童饮食与当前哮喘的关系。

方法

本研究为横断面研究，共纳入了 1000 名来自黎巴嫩公立和私立学校的儿童。共纳入 107 名哮喘患儿进行分析。采用食物频率问卷评估参与者的饮食习惯。

结果

每周食用甜食≥3 次（ORa=5.42）、每周食用白面包≥3 次（ORa=26.38）和每日食用橄榄油（ORa=9.80）与当前哮喘的发生风险增加相关。偶尔饮用碳酸饮料（ORa=0.25）和每周饮用≥3 次（ORa=0.03）与当前哮喘的发生风险降低相关。与从不食用地中海饮食相比，偶尔食用（每周>3 次和每日）和经常食用地中海饮食（ORa=0.23 和 ORa=0.22）与当前哮喘的发生风险降低相关。偶尔食用面包与当前哮喘的发生风险增加显著相关（ORa=8.2），而每日食用面包与当前哮喘的发生风险降低显著相关（ORa=0.336）。此外，偶尔、每周≥3 次和每日食用肉类与当前哮喘的发生风险增加显著相关（ORa=9.6；ORa=5.1 和 ORa=4.5）。偶尔食用垃圾食品与当前哮喘的发生风险降低显著相关（ORa=0.044），而每日食用则与当前哮喘的发生风险增加显著相关。