从艾滋病患者粪便中分离出鸟分枝杆菌-胞内分枝杆菌-瘰疬分枝杆菌复合体。
Isolation of Mycobacterium avium-intracellulare-scrofulaceum complex from faeces of patients with AIDS.
作者信息
Stacey A R
出版信息
Br Med J (Clin Res Ed). 1986 Nov 8;293(6556):1194. doi: 10.1136/bmj.293.6556.1194.
Abstract
Thirty faecal specimens from 22 patients with the acquired immune deficiency syndrome were examined by microscopy after Ziehl-Neelsen staining and by culture after decontamination with sodium hydroxide. Thirteen specimens (from 11 patients) were positive for Mycobacterium avium-intracellulare-scrofulaceum on culture, and only five of these on Ziehl-Neelsen staining. Five of the 11 patients had evidence of disseminated infection. Lipid analysis showed six of the nine strains tested to be indistinguishable. These findings support the theory that the gastrointestinal tract is a portal of entry for the organism.
摘要
对22例获得性免疫缺陷综合征患者的30份粪便标本进行了齐尔-尼尔森染色后显微镜检查，以及用氢氧化钠净化后培养。13份标本（来自11例患者）在培养时鸟分枝杆菌-胞内分枝杆菌-瘰疬分枝杆菌呈阳性，其中只有5份在齐尔-尼尔森染色时呈阳性。11例患者中有5例有播散性感染的证据。脂质分析显示，所检测的9株菌株中有6株无法区分。这些发现支持了胃肠道是该病原体的一个入口的理论。
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