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八放珊瑚:具有多样性生物活性萜类化合物的潜在来源。

Octocorals: Potential Source of Diverse Bioactive Terpenoids.

机构信息

Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, P.O. Box 80260, Jeddah 21589, Saudi Arabia.

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.

出版信息

Molecules. 2019 Apr 8;24(7):1370. doi: 10.3390/molecules24071370.

Abstract

corals are benthic animals, which live in different climatic areas, including temperate, Antarctic and sub-Antarctic waters. They were found to produce different chemical substances with molecular diversity and unique architectures. These metabolites embrace several terpenoidal classes with different functionalities. This wide array of structures supports the productivity of genus . Yet, majority of the reported compounds are still biologically unscreened and require substantial efforts to explore their importance. This review is an entryway to push forward the bio-investigation of this genus. It covers the era from the beginning of reporting metabolites from up to March 2019. Ninety-two metabolites are presented; forty-two sesquiterpenes, twenty-five diterpenes and twenty-five steroids have been reported from sixteen species.

摘要

珊瑚是底栖动物,生活在不同的气候区域,包括温带、南极和亚南极水域。它们被发现能产生具有分子多样性和独特结构的不同化学物质。这些代谢产物包含多种具有不同功能的萜类化合物。这种广泛的结构支持了属的生产力。然而,报道的大多数化合物仍然没有经过生物筛选,需要大量的努力来探索它们的重要性。这篇综述是推动对该属进行生物研究的一个切入点。它涵盖了从开始报道代谢产物到 2019 年 3 月的时期。从 16 个物种中报道了 92 种代谢产物;其中 42 种倍半萜、25 种二萜和 25 种甾体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5991/6479912/796cc0853ba2/molecules-24-01370-g001.jpg

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