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本文引用的文献

1
The association of vitamin D deficiency and glucose control among diabetic patients.糖尿病患者中维生素D缺乏与血糖控制的关联。
Saudi Pharm J. 2017 Dec;25(8):1179-1183. doi: 10.1016/j.jsps.2017.09.001. Epub 2017 Sep 12.
2
The prevalence and determinants of poor glycemic control among adults with type 2 diabetes mellitus in Saudi Arabia.沙特阿拉伯2型糖尿病成年患者血糖控制不佳的患病率及影响因素
Diabetes Metab Syndr Obes. 2018 Jan 31;11:15-21. doi: 10.2147/DMSO.S156214. eCollection 2018.
3
Vitamin D deficiency in Saudi Arabians: A reality or simply hype: A meta-analysis (2008-2015).沙特阿拉伯人的维生素D缺乏:是现实还是仅仅是炒作:一项荟萃分析(2008 - 2015年)
J Family Community Med. 2018 Jan-Apr;25(1):1-4. doi: 10.4103/jfcm.JFCM_73_17.
4
Assessment of gender-related differences in vitamin D levels and cardiovascular risk factors in Saudi patients with type 2 diabetes mellitus.沙特2型糖尿病患者维生素D水平及心血管危险因素的性别差异评估
Saudi J Biol Sci. 2018 Jan;25(1):31-36. doi: 10.1016/j.sjbs.2017.04.001. Epub 2017 Apr 4.
5
11. Older Adults: .11. 老年人: 。
Diabetes Care. 2018 Jan;41(Suppl 1):S119-S125. doi: 10.2337/dc18-S011.
6
6. Glycemic Targets: .6. 血糖目标: 。
Diabetes Care. 2018 Jan;41(Suppl 1):S55-S64. doi: 10.2337/dc18-S006.
7
Factors Associated with Long-Term Control of Type 2 Diabetes Mellitus.与 2 型糖尿病长期控制相关的因素。
J Diabetes Res. 2016;2016:2109542. doi: 10.1155/2016/2109542. Epub 2016 Dec 20.
8
Prevalence and co-prevalence of comorbidities among patients with type 2 diabetes mellitus.2型糖尿病患者中合并症的患病率及共患病率。
Curr Med Res Opin. 2016 Jul;32(7):1243-52. doi: 10.1185/03007995.2016.1168291. Epub 2016 Apr 4.
9
Polypharmacy in the Aging Patient: A Review of Glycemic Control in Older Adults With Type 2 Diabetes.老年患者的多重用药:2型糖尿病老年人血糖控制的综述
JAMA. 2016 Mar 8;315(10):1034-45. doi: 10.1001/jama.2016.0299.
10
Statins and diabetes.他汀类药物与糖尿病
Cardiol Clin. 2015 May;33(2):233-43. doi: 10.1016/j.ccl.2015.02.004.

沙特阿拉伯2型糖尿病患者血糖控制的相关因素。

Factors associated with glycemic control in type 2 diabetic patients in Saudi Arabia.

作者信息

Almetwazi Mansour, Alwhaibi Monira, Balkhi Bander, Almohaini Hissah, Alturki Haya, Alhawassi Tariq, Ata Sondus, AlQahtani Nasser, Mahmoud Mansour, Alshammari Thamir

机构信息

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Medication Safety Research Chair, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

出版信息

Saudi Pharm J. 2019 Mar;27(3):384-388. doi: 10.1016/j.jsps.2018.12.007. Epub 2018 Dec 26.

DOI:10.1016/j.jsps.2018.12.007
PMID:30976182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6438893/
Abstract

OBJECTIVE

To identify factors associated with glycemic control in type 2 diabetes mellitus patients in tertiary academic hospital.

RESEARCH DESIGN AND METHODS

This was a retrospective cross-sectional study of adults with type 2 diabetes mellitus. Data were extracted from the electronic health record (EHR) database for the period from 1st of January to 31st of December 2016. Participants were considered to have a glucose control if the HbA1c level was less than 7% [53 mmol/L]. Descriptive analysis and multivariable logistic regression model were performed to assess the factors associated with glycemic control.

RESULTS

A total of 728 patients were included in the study for which (65%) were female, and about 60% of the sample size was between 45 and 60 years old. Multivariate logistic regression model showed participants older than the age of 65 were less likely to have controlled diabetes compared to the younger participants (OR: 0.53 [CI: 0.30-0.93]). Moreover, those who had hypertension (OR: 0.61 [CI: 0.43-0.86]) and dyslipidemia (OR: 0.53 [CI: 0.38-0.74]) were less likely to have controlled diabetes, while those with asthma (OR: 2.06 [CI: 1.16-3.68]) were more likely to have controlled diabetes. The model also showed that vitamin D deficiency was not associated with glycemic control in type 2 diabetes patients (OR 0.80 [95% CI 0.58-1.12]).

CONCLUSION

These findings highlighted the need for appropriate management in older adult patients to prevent the complication of type 2 diabetes. Furthermore, attention should be exercised for patients with factors associated with poor glycemic control such as hypertension and dyslipidemia.

摘要

目的

确定三级学术医院中2型糖尿病患者血糖控制的相关因素。

研究设计与方法

这是一项针对成年2型糖尿病患者的回顾性横断面研究。数据从2016年1月1日至12月31日期间的电子健康记录(EHR)数据库中提取。如果糖化血红蛋白(HbA1c)水平低于7%[53 mmol/L],则参与者被认为血糖得到控制。进行描述性分析和多变量逻辑回归模型以评估与血糖控制相关的因素。

结果

共有728名患者纳入研究,其中65%为女性,约60%的样本年龄在45至60岁之间。多变量逻辑回归模型显示,与年轻参与者相比,65岁以上的参与者糖尿病得到控制的可能性较小(比值比:0.53[置信区间:0.30 - 0.93])。此外,患有高血压(比值比:0.61[置信区间:0.43 - 0.86])和血脂异常(比值比:0.53[置信区间:0.38 - 0.74])的患者糖尿病得到控制的可能性较小,而患有哮喘的患者(比值比:2.06[置信区间:1.16 - 3.68])糖尿病得到控制的可能性较大。该模型还表明,维生素D缺乏与2型糖尿病患者的血糖控制无关(比值比0.80[95%置信区间0.58 - 1.12])。

结论

这些发现凸显了对老年患者进行适当管理以预防2型糖尿病并发症的必要性。此外,对于伴有血糖控制不佳相关因素(如高血压和血脂异常)的患者应予以关注。