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伴有腹胀的急性胰腺炎,脂肪酶和淀粉酶正常:一例报告。

Acute pancreatitis with abdominal bloating and distension, normal lipase and amylase: A case report.

作者信息

Wang Yuan-Yu, Qian Zhen-Yuan, Jin Wei-Wei, Chen Ke, Xu Xiao-Dong, Mou Yi-Ping, Zhang Wei

机构信息

Departments of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, PR China and Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, PR China.

出版信息

Medicine (Baltimore). 2019 Apr;98(15):e15138. doi: 10.1097/MD.0000000000015138.

Abstract

RATIONALE

Acute pancreatitis is an inflammatory disorder of the pancreas, and its correct diagnosis is an area of interest for clinicians. In accordance with the revised Atlanta classification, acute pancreatitis can be diagnosed if at least 2 of the following 3 criteria are fulfilled: abdominal pain; serum lipase (or amylase) activity at least 3 times the upper limit of normal; or characteristic findings of acute pancreatitis on contrast-enhanced computed tomography (CT) or, less often, magnetic resonance imaging or transabdominal ultrasonography. Diagnostic imaging is essential in patients with no or slight enzyme elevation. If enzymes are normal in cases with abdominal distension, there is clinical doubt about the diagnosis of acute pancreatitis, so an early CT scan should be obtained and other life-threatening disorders excluded.

PATIENT CONCERNS

A 50-year-old male presented with a 1-day history of abdominal bloating and distension. On physical examination, abdominal bulging and mild epigastric tenderness were detected. Laboratory evaluation showed normal amylase and lipase. There was no abnormality on abdominal ultrasound or CT of the abdomen and pelvis. On the fourth day of admission, CT of the abdomen and pelvis showed a hypodense lesion in the pancreas surrounded by a moderate amount of peripancreatic fluid.

DIAGNOSES

In accordance with the revised Atlanta classification, acute pancreatitis was diagnosed, based on the presence of abdominal pain, and the results of the CT scan of the abdomen and pelvis.

INTERVENTIONS

The patient was treated with fasting, gastrointestinal decompression bowel rest, intravenous rehydration, and somatostatin.

OUTCOMES

After 2 days of treatment, his abdominal distension was significantly relieved, and the patient was discharged on the seventh day of admission. At the 3-month follow-up, the patient had no recurrence of pancreatitis.

LESSONS

This case of abdominal distension could not be explained by common causes, such as ascites, bowel edema, hematoma, bowel distension, or ileus, which led us to suspect pancreatitis.

摘要

理论依据

急性胰腺炎是胰腺的一种炎症性疾病,其正确诊断是临床医生关注的领域。根据修订后的亚特兰大分类标准,如果满足以下3项标准中的至少2项,即可诊断为急性胰腺炎:腹痛;血清脂肪酶(或淀粉酶)活性至少为正常上限的3倍;或在增强计算机断层扫描(CT)上有急性胰腺炎的特征性表现,较少情况下在磁共振成像或经腹超声检查中有此类表现。对于酶升高不明显或无酶升高的患者,诊断性影像学检查至关重要。如果腹胀患者的酶正常,临床上对急性胰腺炎的诊断存在疑问,应尽早进行CT扫描并排除其他危及生命的疾病。

患者情况

一名50岁男性,有1天的腹胀病史。体格检查发现腹部膨隆,上腹部轻度压痛。实验室检查显示淀粉酶和脂肪酶正常。腹部超声及腹部和盆腔CT均未见异常。入院第4天,腹部和盆腔CT显示胰腺有一个低密度病变,周围有中等量的胰周液。

诊断

根据修订后的亚特兰大分类标准,基于腹痛以及腹部和盆腔CT检查结果,诊断为急性胰腺炎。

干预措施

患者接受禁食、胃肠减压、肠道休息、静脉补液和生长抑素治疗。

结果

治疗2天后,腹胀明显缓解,患者于入院第7天出院。3个月随访时,患者胰腺炎未复发。

经验教训

该例腹胀不能用腹水、肠水肿、血肿、肠扩张或肠梗阻等常见原因解释,这使我们怀疑为胰腺炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80fc/6485828/fe3ca189e91d/medi-98-e15138-g002.jpg

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