Interdisciplinary Laboratory of Biosciences and Celiac Disease Research Center, School of Medicine, University of Brasilia, Brasilia 70910-900, Brazil.
Department of Nutrition, School of Health Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
Nutrients. 2019 Apr 4;11(4):781. doi: 10.3390/nu11040781.
This study aimed to translate, culturally adapt, validate, and apply a questionnaire to the Brazilian non-celiac gluten sensitive (NCGS) population. We also aimed to estimate the prevalence of symptoms which affect Brazilian NCGS. The Brazilian Portuguese version of the NCGS questionnaire was developed according to revised international guidelines. Five-hundred-and-fourty-three participants responded the NCGS questionnaire. We evaluated the reproducibility and validity of the questionnaire which presents valid measures of reproducibility. This is the first specific self-reported validated questionnaire for NCGS patients in Brazilian Portuguese, and the first nationwide characterization of self-reported NCGS in Brazilian adults. Most respondents were female (92.3%), and the main intestinal symptoms reported were bloating and abdominal pain. The most frequent extraintestinal symptoms were lack of wellbeing, tiredness, and depression. We expect that the present study will provide a picture of Brazilian individuals with suspected NCGS, which could help health professionals and governmental institutions in developing effective strategies to improve the treatment and diagnosis of Brazilian NCGS.
本研究旨在将非乳糜泻麸质敏感（NCGS）问卷翻译成巴西葡萄牙语并进行文化调适、验证和应用，同时估计影响巴西 NCGS 人群的症状的流行率。根据修订后的国际指南，我们制定了巴西葡萄牙语版的 NCGS 问卷。共有 543 名参与者对 NCGS 问卷做出了回应。我们评估了问卷的可重复性和有效性，该问卷具有可重复使用的有效测量方法。这是首个针对巴西葡萄牙语 NCGS 患者的特定自我报告验证问卷，也是首个针对巴西成年人的全国性自我报告 NCGS 特征描述。大多数受访者为女性（92.3%），报告的主要肠道症状为腹胀和腹痛。最常见的肠外症状是不适、疲劳和抑郁。我们希望本研究将为巴西疑似 NCGS 个体提供一个整体画面，这有助于卫生专业人员和政府机构制定有效的策略，以改善巴西 NCGS 的治疗和诊断。
