Coppock J S, Hardman J M, Bacon P A, Woods K L, Kendall M J
Postgrad Med J. 1986 Jan;62(723):15-8. doi: 10.1136/pgmj.62.723.15.
An objective response to topical glyceryl trinitrate was shown by digital plethysmography in a study of 17 patients with Raynaud's phenomenon. Improvement was significant (P less than 0.005) in those in whom the disease was secondary to an underlying connective tissue disorder. The response suggests that the effect of this drug is mediated locally.
在一项针对17例雷诺现象患者的研究中,通过数字体积描记法显示了对局部应用硝酸甘油的客观反应。在疾病继发于潜在结缔组织疾病的患者中,改善情况显著(P<0.005)。该反应表明这种药物的作用是局部介导的。