Pre-Treatment and Finishing of Cellulosic Fabric Department, Textile Research Division, National Research Center, 33 El-Behooth St, Dokki, Giza 12311, Egypt.
Pre-Treatment and Finishing of Cellulosic Fabric Department, Textile Research Division, National Research Center, 33 El-Behooth St, Dokki, Giza 12311, Egypt.
Int J Biol Macromol. 2019 Jul 15;133:583-591. doi: 10.1016/j.ijbiomac.2019.04.065. Epub 2019 Apr 18.
The current study was set to prepare a delivery system based on a mixture of biodegradable polymeric hydrogel (i.e., carrageenan (κ-CAR) and β-cyclodextrin (β-CD)) for encapsulating honey bee propolis extract (HBP). The crosslinking agent; glyoxal was incorporated to increase the insolubility of the HBP-loaded hydrogel to fit the cotton fabric treatments. The synthesized hydrogels were fully characterized to examine their surface and internal morphology and to visualize the chemical interaction between κ-CAR and β-CD via SEM and FTIR techniques. The SEM pictures ensured the existent of many pores within the formed hydrogel. The swelling properties of κ-CAR/β-CD/HBP were also studied in terms of glyoxal and HBP concentrations which displayed water holding with higher mechanical properties. Furthermore, in vitro release assessment of HBP from κ-CAR/β-CD hydrogel was also studied at pH 7.6. Therefore, κ-CAR/β-CD/HBP hydrogel was successfully used as fining compound for the cationized cotton fabrics. The data obtained emphasized that the surface of cationized cotton fabrics was deposited and penetrated with a film of κ-CAR/β-CD/HBP. In addition, the antimicrobial activity of the treated cationized fabric was evaluated against many species of bacteria and fungus producing highly inhibition zone at lower concentrations of HBP. Accordingly, the cationized cotton fabric treated with κ-CAR/β-CD/HBP has a high potential in the wound healing fabrics.
本研究旨在制备一种基于可生物降解聚合物水凝胶（即卡拉胶（κ-CAR）和β-环糊精（β-CD））的递送系统，用于包封蜂蜜蜂胶提取物（HBP）。交联剂；乙二醛的加入增加了载有 HBP 的水凝胶的不溶性，以适应棉织物处理。合成的水凝胶进行了全面的表征，以检查其表面和内部形态，并通过 SEM 和 FTIR 技术可视化 κ-CAR 和 β-CD 之间的化学相互作用。SEM 图片确保了形成的水凝胶内存在许多孔。还研究了 κ-CAR/β-CD/HBP 的溶胀性能，包括乙二醛和 HBP 浓度，显示出具有更高机械性能的持水能力。此外，还研究了 κ-CAR/β-CD 水凝胶在 pH 7.6 下从 HBP 的体外释放情况。因此，κ-CAR/β-CD/HBP 水凝胶成功地用作阳离子化棉织物的精制化合物。获得的数据强调，阳离子化棉织物的表面沉积并渗透有一层 κ-CAR/β-CD/HBP。此外，还评估了处理过的阳离子化织物对多种细菌和真菌的抗菌活性，在较低浓度的 HBP 下产生了高度的抑菌区。因此，用 κ-CAR/β-CD/HBP 处理的阳离子化棉织物在伤口愈合织物方面具有很大的潜力。
