Alenius Minna, Koskinen Sanna, Hallikainen Ilona, Ngandu Tiia, Lipsanen Jari, Sainio Päivi, Tuulio-Henriksson Annamari, Hänninen Tuomo
Department of Psychology and Logopedics, Helsinki University, Helsinki, Finland.
Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.
Dement Geriatr Cogn Dis Extra. 2019 Feb 1;9(1):11-23. doi: 10.1159/000495657. eCollection 2019 Jan-Apr.
BACKGROUND/AIMS: To detect cognitive decline in older adults, measures of verbal fluency and verbal memory are widely used. Less is known about performance in these measures in younger persons or according to education level and gender. We investigated cognitive performance according to age, education and gender among cognitively healthy adults aged 30-100 years.
The study population comprised 4,174 cognitively healthy persons participating in the nationally representative Finnish Health 2011 survey. Cognitive assessment included verbal fluency, word list memory, word list recall and word list savings from the Consortium to Establish a Registry for Alzheimer's Disease neuropsychological battery.
Total variance in the cognitive test performance explained by age, education and gender varied from 12.3 to 31.2%. A decreasing trend in cognitive performance existed in all subtests by advancing age, with differences appearing between 50 and 55 years. Persons with the highest-education level performed best for all measures. For the participants < 55 years, education explained part of the variance, while age and gender did not.
When assessing cognition, age and education should be accounted for in more detail in research and clinical practice. Additionally, the cohort effect and its potential impact on the renewal cycle of future normative values for cognitive tests should be considered.
背景/目的:为了检测老年人的认知衰退情况,语言流畅性和语言记忆的测量方法被广泛使用。对于年轻人在这些测量方法中的表现,或者根据教育水平和性别进行的表现了解较少。我们调查了30至100岁认知健康成年人的认知表现与年龄、教育程度和性别的关系。
研究人群包括4174名参与具有全国代表性的2011年芬兰健康调查的认知健康者。认知评估包括来自阿尔茨海默病神经心理学联合登记协会电池的语言流畅性、单词表记忆、单词表回忆和单词表节省。
由年龄、教育程度和性别解释的认知测试表现的总方差在12.3%至31.2%之间。随着年龄增长,所有子测试中的认知表现都存在下降趋势,在50至55岁之间出现差异。教育水平最高的人在所有测量中表现最佳。对于年龄小于55岁的参与者,教育解释了部分方差,而年龄和性别则没有。
在研究和临床实践中评估认知时,应更详细地考虑年龄和教育程度。此外,应考虑队列效应及其对未来认知测试规范值更新周期的潜在影响。