Koevska Valentina, Nikolikj-Dimitrova Erieta, Mitrevska Biljana, Gjeracaroska-Savevska Cvetanka, Gocevska Marija, Kalcovska Biljana
Institute of Physical Medicine and Rehabilitation, Faculty of Medicine, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
Open Access Maced J Med Sci. 2019 Apr 14;7(7):1160-1165. doi: 10.3889/oamjms.2019.271. eCollection 2019 Apr 15.
Osteoporosis is a systemic skeletal disease characterised by a low bone density and microarchitectural deterioration of bone tissue leading to decrease of its strength and increased risk of fracture. Drug therapy decreases the risk of fracture, thus influencing on the mechanism of bone remodelling. Non-pharmacological interventions include specific exercises for osteoporosis that improve muscle strength and balance, decrease pain and improve quality of life.
To compare the quality of life in patients with postmenopausal osteoporosis who practice exercises with those who do not practice on the beginning and after a year.
A randomised Single-blind randomised controlled prospective trial study, which included 92 women with postmenopausal osteoporosis diagnosed and treated at the Institute of Physical Medicine and Rehabilitation in Skopje, Republic of Macedonia. Patients were randomly assigned to three groups: the first group of patients with exercises and physical modalities (gr. I), the second group with exercises (gr. II), and the third control group of patients who did not practice exercises (gr. III). Exercises were practised 3 times a week; each exercise was repeated for 5-8 times. Patients regularly took bisphosphonates, calcium and vitamin D. The follow-up period lasted for one year. Quality of life was determined with a specific questionnaire Qualeffo-41.
The results showed, significant statistical difference in terms of pain, physical activity, social life, the perception of own health were shown between the groups (p < 0.0001), only in term of mental function were no significant (p < 0.3).
Patients who practice exercises for osteoporosis have a significantly better quality of life than patients who do not perform exercises.
骨质疏松症是一种全身性骨骼疾病，其特征是骨密度低和骨组织微结构恶化，导致骨强度下降和骨折风险增加。药物治疗可降低骨折风险，从而影响骨重塑机制。非药物干预措施包括针对骨质疏松症的特定锻炼，可增强肌肉力量和平衡能力、减轻疼痛并提高生活质量。
比较绝经后骨质疏松症患者在开始锻炼和锻炼一年后，锻炼组与未锻炼组的生活质量。
一项随机单盲随机对照前瞻性试验研究，纳入了92名在马其顿共和国斯科普里物理医学与康复研究所诊断和治疗的绝经后骨质疏松症女性。患者被随机分为三组：第一组为进行锻炼和物理治疗的患者（第一组），第二组为进行锻炼的患者（第二组），第三组为不进行锻炼的对照组患者（第三组）。每周锻炼3次；每个动作重复5 - 8次。患者定期服用双膦酸盐、钙和维生素D。随访期为一年。使用特定问卷Qualeffo - 41确定生活质量。
结果显示，各组之间在疼痛、身体活动、社交生活、对自身健康的认知方面存在显著统计学差异（p < 0.0001），仅在心理功能方面无显著差异（p < 0.3）。
进行骨质疏松症锻炼的患者生活质量明显优于不进行锻炼的患者。
