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从三叶木通废料中开发出具有抗菌作用的果胶,以加速伤口愈合。

Development of antibacterial pectin from Akebia trifoliata var. australis waste for accelerated wound healing.

机构信息

State Key Laboratory of Food Science and Technology, Nanchang University, No. 235 Nanjing East Road, Nanchang, 330047, China.

Department of Biological and Agricultural Engineering, University of Arkansas, Fayetteville, AR, 72701, USA.

出版信息

Carbohydr Polym. 2019 Aug 1;217:58-68. doi: 10.1016/j.carbpol.2019.03.071. Epub 2019 Mar 21.

DOI:10.1016/j.carbpol.2019.03.071
PMID:31079685
Abstract

The fruit of Akebia trifoliata var. australis can be consumed as food. However, the peel of this fruit is typically regarded as waste. The application of such waste can create opportunities to produce new and valuable by-products. Herein, we have shown that citric acid extracted pectin (CEP) from Akebia trifoliata var. australis peel has good water solubility and high galacturonic units, which helps reduce AgNO into Ag nanoparticles (CEP-AgNPs) through a one-step, eco-friendly process. The resulting CEP-AgNPs showed sustained release of Ag and remarkable antibacterial activity. Subsequently, the CEP-AgNPs were processed into a CEP-Ag sponge with excellent water absorption and prolonged water retention properties. The CEP-Ag sponge could support the cell adhesion and proliferation. Most importantly, the sponge effectively facilitated a moist environment with bacterial disinfection capability which accelerated the healing of infected wounds. Thus, CEP-Ag sponge, a sustainable and high value by-product, was obtained from food waste.

摘要

三叶木通的果实可食用。然而,这种果实的果皮通常被视为废物。废物的应用可以为生产新的有价值的副产品创造机会。在这里,我们表明,从三叶木通果皮中提取的柠檬酸果胶 (CEP) 具有良好的水溶性和高半乳糖醛酸单元,有助于通过一步、环保的过程将 AgNO 还原成 Ag 纳米颗粒 (CEP-AgNPs)。所得的 CEP-AgNPs 表现出 Ag 的持续释放和显著的抗菌活性。随后,将 CEP-AgNPs 加工成具有优异吸水性和延长保水性能的 CEP-Ag 海绵。CEP-Ag 海绵可以支持细胞黏附和增殖。最重要的是,该海绵有效地营造了一个具有细菌消毒能力的湿润环境,加速了感染伤口的愈合。因此,从食品废物中获得了一种可持续且高附加值的 CEP-Ag 海绵副产品。

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