葡萄糖转运蛋白1（GLUT-1）和己糖激酶-II（HK-II）表达在头颈癌生物学行为中的作用
Roles of GLUT-1 and HK-II expression in the biological behavior of head and neck cancer.
作者信息
Yang Hang, Zhong Jiang-Tao, Zhou Shui-Hong, Han He-Ming
机构信息
Department of Otorhinolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.
Present Address: Department of Otorhinolaryngology, The People's Hospital of Jiangshan City, Jiangshan, Zhejiang, 324100, China.
出版信息
Oncotarget. 2019 Apr 30;10(32):3066-3083. doi: 10.18632/oncotarget.24684.
The Warburg effect plays an important role in the proliferation and invasion of malignant tumors. Glucose transporter 1 and hexokinase II are two key energy transporters involved in mediating the Warburg effect. This review will analyze the mechanisms of these two markers in their effects on the biological behavior of head and neck cancer.
瓦伯格效应在恶性肿瘤的增殖和侵袭中起着重要作用。葡萄糖转运蛋白1和己糖激酶II是介导瓦伯格效应的两个关键能量转运体。本文综述将分析这两种标志物对头颈部癌生物学行为影响的机制。
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