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熔融静电纺丝支架设计对 X 射线微断层扫描法确定的孔隙率的影响。

The Impact of Melt Electrowritten Scaffold Design on Porosity Determined by X-Ray Microtomography.

机构信息

1 Department for Functional Materials in Medicine and Dentistry, Bavarian Polymer Institute, University Hospital Würzburg, Würzburg, Germany.

2 Chair of X-Ray Microscopy (LRM), University of Würzburg, Würzburg, Germany.

出版信息

Tissue Eng Part C Methods. 2019 Jun;25(6):367-379. doi: 10.1089/ten.TEC.2018.0373.

Abstract

Melt electrowriting is an AM technology that bridges the gap between solution electrospinning and melt microextrusion technologies. It can be applied to biomaterials and tissue engineering by making a spectrum of scaffolds with various laydown patterns at dimensions not previously studied. Using submicrometer X-ray tomography, a "fingerprint" of porosity for such scaffolds can be obtained and used as an important measure for quality control, to ensure that the scaffold fabricated is the one designed and allows the selection of specific scaffolds based on desired porosities.

摘要

熔融静电纺丝是一种 AM 技术,它连接了溶液静电纺丝和熔融微挤出技术之间的空白。通过制造各种具有不同铺设模式的支架,可以将其应用于生物材料和组织工程,其尺寸是以前未曾研究过的。使用亚微米 X 射线断层扫描,可以获得这种支架的孔隙率“指纹”,并将其用作重要的质量控制措施,以确保制造的支架是设计的支架,并允许根据所需的孔隙率选择特定的支架。

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