Kang Hee-Young, Choi Eun-Young
a Department of Nursing, Chosun University , 309, Pilmundaero, Dong-gu, Gwangju 61452 , South Korea.
b Department of Nursing, Chosun Nursing College , 309-2, Pilmundaero, Dong-gu, Gwangju 61453 , South Korea.
Contemp Nurse. 2019 Apr-Jun;55(2-3):109-121. doi: 10.1080/10376178.2019.1623699. Epub 2019 May 30.
Over the course of repetitive and long-term chemotherapy treatment, multiple myeloma (MM) patients experience physical and psychological problems and side effects. The objective of this study was to investigate the levels of pain, uncertainty, social support, anxiety, depression, and quality of life (QOL) receiving chemotherapy for MM patients and to identify psychosocial factors influencing their QOL. A cross-sectional descriptive design was used. A total of 110 MM patients receiving chemotherapy were recruited into the study. The data were collected by personal interviews using questionnaires and were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation, and hierachial multiple regression analysis. Global health status QOL was explained by uncertainty, anxiety, and depression. Functional QOL was explained by age, uncertainty, and anxiety. Symptom QOL was explained by pain, and depression. Uncertainty, anxiety and depression were the strongest predictive factors. To improve QOL of patients with MM, nurses should focus on the factors identified in this study when doing nursing care. This study confirmed psychological difficulties such as uncertainty, anxiety and depression affecting quality of life of MM patients receiving chemotherapy.
在重复且长期的化疗过程中，多发性骨髓瘤（MM）患者会经历身体和心理问题以及副作用。本研究的目的是调查接受化疗的MM患者的疼痛、不确定性、社会支持、焦虑、抑郁及生活质量（QOL）水平，并确定影响其生活质量的心理社会因素。采用横断面描述性设计。共有110名接受化疗的MM患者被纳入研究。通过问卷调查进行个人访谈收集数据，并使用描述性统计、t检验、单因素方差分析、Pearson相关性分析和层次多元回归分析进行分析。总体健康状况生活质量由不确定性、焦虑和抑郁来解释。功能生活质量由年龄、不确定性和焦虑来解释。症状生活质量由疼痛和抑郁来解释。不确定性、焦虑和抑郁是最强的预测因素。为提高MM患者的生活质量，护士在进行护理时应关注本研究中确定的因素。本研究证实了不确定性、焦虑和抑郁等心理困难会影响接受化疗的MM患者的生活质量。
