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分化的T细胞亚群之间的关系。IV. 对异种移植物的迟发性足垫反应的优先诱导及其抗辐射特性。

Relationships among differentiated T-cell subpopulations. IV. Preferential induction of delayed footpad reaction to xenografts and its radioresistant nature.

作者信息

Terasaka R, Nomoto K, Himeno K, Takeya T

出版信息

Immunology. 1979 Apr;36(4):699-705.

PMID:312268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1457669/
Abstract

Immune response in mice to xenogeneic cells was characterized by positive delayed footpad reaction and negative macrophage migration inhibition. Mice immunized with allogeneic cells exhibited negative delayed footpad reaction and positive macrophage migration inhibition. Cytotoxic T lymphocytes were detected only in mice immunized with allogeneic tumour cells. Delayed footpad reaction against xenogeneic cells was radioresistant and the immune lymphocytes responsible for such a reaction were presumed to have some relation to xenograft rejection.

摘要

小鼠对异种细胞的免疫反应表现为足垫迟发型反应阳性和巨噬细胞移动抑制阴性。用同种异体细胞免疫的小鼠表现为足垫迟发型反应阴性和巨噬细胞移动抑制阳性。仅在用同种异体肿瘤细胞免疫的小鼠中检测到细胞毒性T淋巴细胞。针对异种细胞的足垫迟发型反应具有放射抗性，推测负责这种反应的免疫淋巴细胞与异种移植排斥反应有某种关系。

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Immune response to syngeneic or autologous testicular cells in mice. I. Augmented delayed footpad reaction in cyclophosphamide-treated mice.小鼠对同基因或自体睾丸细胞的免疫反应。I. 环磷酰胺处理小鼠中增强的迟发型足垫反应。
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Immunology. 1979 Dec;38(4):773-9.

本文引用的文献

1
IN VITRO STUDIES ON HOMOGRAFT SENSITIVITY.同种移植敏感性的体外研究。
Nature. 1965 Feb 27;205:916-7. doi: 10.1038/205916a0.
2
In vitro cell migration as a model for delayed hypersensitivity.体外细胞迁移作为迟发型超敏反应的模型。
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Anxiety and verbal conditioning in children.儿童的焦虑与言语条件作用
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The migration-inhibitory factor (MIF). Effect of antilymphocytic serum on formation and performance of MIF in murine in vitro experiments.迁移抑制因子（MIF）。抗淋巴细胞血清对小鼠体外实验中MIF形成及功能的影响。
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Immunopotentiation with BCG. II. Modulation of the response to sheep red blood cells.卡介苗免疫增强作用。II. 对绵羊红细胞反应的调节
J Natl Cancer Inst. 1973 Nov;51(5):1669-76. doi: 10.1093/jnci/51.5.1669.
6
Cell interactions in humoral and cell-mediated immunity.体液免疫和细胞介导免疫中的细胞相互作用。
Nat New Biol. 1972 Jul 26;238(82):114-6. doi: 10.1038/newbio238114a0.
7
Effector mechanisms of cell-mediated immunity to xenogeneic cell antigens.针对异种细胞抗原的细胞介导免疫的效应机制。
J Immunol. 1974 Jul;113(1):201-8.
8
Experiments on thermodifferential chemotherapy with thoracotomy for blood-borne pulmonary metastasis in rats.大鼠血行性肺转移开胸热差化疗实验
Gan. 1977 Apr;68(2):165-74.
9
Involvement of lymphocyte mediators in the rejection of a murine tumor allograft.淋巴细胞介质在小鼠肿瘤同种异体移植排斥反应中的作用。
Cell Immunol. 1977 May;30(2):261-71. doi: 10.1016/0008-8749(77)90070-3.
10
Relationships among differentiated T-cell subpopulations. I. Dissociated development of tuberculin type hypersensitivity, Jones-Mote type hypersensitivity and activation of helper function.分化的T细胞亚群之间的关系。I. 结核菌素型超敏反应、琼斯-莫特型超敏反应与辅助功能激活的解离性发育。
Immunology. 1976 Jul;31(1):101-10.

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