嗜肺军团菌各菌种及血清群之间的交叉反应性。
Cross-reactivity among Legionella species and serogroups.
作者信息
Pelaz C, García Albert L, Bourgon C M
机构信息
Centro Nacional de Microbiología, Virología e Inmunología Sanitarias, Madrid, Spain.
出版信息
Epidemiol Infect. 1987 Dec;99(3):641-6. doi: 10.1017/s0950268800066498.
Abstract
Cross-reactions of 17 members of the family Legionellaceae were studied by four different serological techniques: immunofluorescence (IF), slide agglutination (SA), microagglutination (MA) and immunodiffusion (ID), using antigens and rabbit antisera prepared in our laboratory. Results obtained corresponded closely with those described by other authors, especially for IF and SA. The 17 antigens were further tested by IF with a panel of sera previously diagnosed as positive for legionella. A high number of positive reactions with several of the antigens tested were found, half of them being positive for Legionella pneumophila serogroup 1, usually in combination with other serogroups or species. The remaining sera presented a great variety of patterns combining different antigens.
摘要
利用我们实验室制备的抗原和兔抗血清，通过四种不同的血清学技术：免疫荧光法（IF）、玻片凝集法（SA）、微量凝集法（MA）和免疫扩散法（ID），研究了军团菌科17个成员的交叉反应。获得的结果与其他作者描述的结果密切相符，尤其是免疫荧光法和玻片凝集法。用一组先前诊断为军团菌阳性的血清，通过免疫荧光法对这17种抗原进行了进一步检测。发现所检测的几种抗原出现大量阳性反应，其中一半对嗜肺军团菌血清1型呈阳性，通常与其他血清型或菌种组合。其余血清呈现出结合不同抗原的多种模式。
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