Department of Biomedical Engineering, Wayne State University, Detroit, MI 48201, USA.
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Sensors (Basel). 2019 Jun 24;19(12):2815. doi: 10.3390/s19122815.
The marked increase in the incidence of melanoma coupled with the rapid drop in the survival rate after metastasis has promoted the investigation into improved diagnostic methods for melanoma. High-frequency ultrasound (US), optical coherence tomography (OCT), and photoacoustic imaging (PAI) are three potential modalities that can assist a dermatologist by providing extra information beyond dermoscopic features. In this study, we imaged a swine model with spontaneous melanoma using these modalities and compared the images with images of nearby healthy skin. Histology images were used for validation.
黑色素瘤发病率的显著增加，加上转移后生存率的迅速下降，促使人们研究改进黑色素瘤的诊断方法。高频超声（US）、光学相干断层扫描（OCT）和光声成像（PAI）是三种潜在的方式，可以通过提供超出皮肤镜特征的额外信息来帮助皮肤科医生。在本研究中，我们使用这些方式对患有自发性黑色素瘤的猪模型进行了成像，并将图像与附近健康皮肤的图像进行了比较。组织学图像用于验证。
