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每日咖啡摄入量与自杀意念的关系。

Relationship between daily coffee intake and suicidal ideation.

机构信息

Department of Occupational & Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Department of Psychiatry, Hanyang University Medical Center, 222-1, Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea.

出版信息

J Affect Disord. 2019 Sep 1;256:468-472. doi: 10.1016/j.jad.2019.06.023. Epub 2019 Jun 22.

Abstract

OBJECTIVE

Caffeine is the most widely-used psychoactive substance in the world. The present study investigates the relationship between caffeine intake and suicide risk according to gender.

METHOD

Analysis of the Kangbuk Samsung Cohort Study (KSCS) data from 80,173 individuals was performed using Chi-square tests and t-tests to determine the relationships between psychosocial constructs and gender. The relationship between caffeine intake and suicidal ideation was analyzed by obtaining odds ratios with multivariate logistic regression in which depression and sleep problems were adjusted for age.

RESULTS

In both men and women with suicidal ideation, the proportion of those who consume four or more cups of coffee per day was highest among the groups of various coffee intake levels. The results on the relationship between daily coffee intake and suicidal ideation revealed that suicide risk was high in both men and women who consume four or more cups of coffee a day. However, once the age, depression and sleep problems were adjusted for, suicide risk decreased in women of 1-4 cups of coffee intake per day, whereas no change was observed in men.

CONCLUSION

Regardless of psychiatric problems such as depression or sleep problems, regular and moderate caffeine intake likely reduces suicide risk as well as depression in women.

摘要

目的

咖啡因是世界上使用最广泛的精神活性物质。本研究根据性别调查了咖啡因摄入与自杀风险之间的关系。

方法

对来自 80173 人的康伯三星队列研究(KSCS)数据进行分析,使用卡方检验和 t 检验确定社会心理结构与性别之间的关系。通过多元逻辑回归获得优势比,调整年龄、抑郁和睡眠问题来分析咖啡因摄入与自杀意念之间的关系。

结果

在有自杀意念的男性和女性中,每天饮用四杯或更多咖啡的人群在各种咖啡摄入量组中比例最高。每日咖啡摄入量与自杀意念之间的关系结果表明,每天饮用四杯或更多咖啡的男性和女性的自杀风险较高。然而,在调整年龄、抑郁和睡眠问题后,每天饮用 1-4 杯咖啡的女性自杀风险降低,而男性则没有变化。

结论

无论是否存在抑郁或睡眠等精神问题,有规律和适度的咖啡因摄入可能会降低女性的自杀风险和抑郁。

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