老年 PTSD 退伍军人运动训练的初步随机对照试验。
Pilot randomized controlled trial of exercise training for older veterans with PTSD.
机构信息
Geriatric Research, Education, and Clinical Center, VA Durham Healthcare System, 508 Fulton St., Durham, NC, 27705, USA.
Department of Medicine, Duke University, 3600 Duke Medicine Circle, Durham, NC, 27710, USA.
出版信息
J Behav Med. 2020 Aug;43(4):648-659. doi: 10.1007/s10865-019-00073-w. Epub 2019 Jul 1.
Exercise training positively impacts mental health, yet remains untested in older adults with posttraumatic stress disorder (PTSD). We conducted a randomized controlled pilot trial to test the feasibility and acceptability of exercise training in older veterans with PTSD. Fifty-four veterans ≥ 60 years, with a DSM-V diagnosis of PTSD, were randomized to supervised exercise (n = 36) or wait-list (WL; n = 18). Primary outcomes included recruitment rates, attendance, satisfaction, and retention. Secondary outcomes included changes in PTSD symptoms, depression, health-related quality of life, and sleep quality; assessed at baseline and 12 weeks. There were no adverse events. Attrition was minimal (14%), and adherence to the exercise intervention was high (82%). Clinically significant improvements in PTSD and related conditions were observed following exercise (Cohen's d = 0.36-0.81). Exercise training is safe and acceptable in older adults with PTSD, may improve PTSD symptoms, and broadly impacts PTSD-related conditions. Future definitive trials are warranted.
运动训练对心理健康有积极影响，但在患有创伤后应激障碍（PTSD）的老年人中尚未得到验证。我们进行了一项随机对照试验，以测试运动训练对患有 PTSD 的老年退伍军人的可行性和可接受性。54 名年龄在 60 岁及以上、DSM-V 诊断为 PTSD 的退伍军人被随机分配到监督运动组（n=36）或候补名单组（WL；n=18）。主要结果包括招募率、出勤率、满意度和保留率。次要结果包括 PTSD 症状、抑郁、与健康相关的生活质量和睡眠质量的变化；在基线和 12 周时进行评估。没有不良事件。脱落率很低（14%），对运动干预的依从性很高（82%）。运动后 PTSD 及相关疾病有明显改善（Cohen's d=0.36-0.81）。运动训练在患有 PTSD 的老年人中是安全且可接受的，可能改善 PTSD 症状，并广泛影响与 PTSD 相关的疾病。未来需要进行明确的试验。
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