Meier Nathan, Hatch Cameron, Nagalakshmi Ugrappa, Dinesh-Kumar Savithramma P
Department of Plant Biology and The Genome Center, College of Biological Sciences, University of California, Davis, CA, 95616, USA.
Mol Plant Pathol. 2019 Sep;20(9):1185-1190. doi: 10.1111/mpp.12839. Epub 2019 Jul 8.
The intracellular nucleotide-binding domain leucine-rich repeat (NLR) class of immune receptors plays an important role in plant viral defence. Plant NLRs recognize viruses through direct or indirect association of viral proteins, triggering a downstream defence response to prevent viral proliferation and movement within the plant. This review focuses on current knowledge of intracellular perception of viral pathogens, activation of NLRs and the downstream signalling components involved in plant viral defence.
细胞内核苷酸结合结构域富含亮氨酸重复序列（NLR）类免疫受体在植物病毒防御中起重要作用。植物NLR通过与病毒蛋白直接或间接结合来识别病毒，触发下游防御反应以防止病毒在植物体内增殖和移动。本综述聚焦于目前关于植物细胞内对病毒病原体的感知、NLR的激活以及植物病毒防御中涉及的下游信号传导成分的知识。
