Department of Sanitary Engineering, Faculty of Public Health, Mahidol University , Bangkok , Thailand.
Department of Public Health Nursing, Faculty of Public Health, Mahidol University , Bangkok , Thailand.
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2019;54(13):1269-1276. doi: 10.1080/10934529.2019.1637207. Epub 2019 Jul 11.
The study determined concentrations of and estimated human exposure to house dust-ingested phthalates from 99 homes in Bangkok, Thailand. Phthalates in dust collected using a handheld vacuum cleaner was analyzed by gas chromatography/mass spectrometry revealing a median content of 3,477 µg g, range 753-13,810 µg g, with di-2-ethylhexylphthalate (DEHP) having the highest level (median = 1,739 µg g, range 467-8,172 µg g) followed by di-iso-nonyl phthalate (DiNP) (median = 611 µg g, range 15.2-11,052 µg g). DEHP in house dust from multi-family apartments with polyvinyl (PVC) floor material ( = 34), multi-family apartments without PVC floor material ( = 55) and single family houses without PVC floor material ( = 10) was median and range 3,009 and 568-6,898; 1,479 and range 467-8,172 and 1,207 µg g and 611-3518 µg g, respectively. At high-end house dust DEHP level, preschool children in all three types of homes were exposed above US Environment Protection Agency reference dose (20 µg g). The results suggest phthalate-containing house products constitute a likely major source of phthalates in indoor home environment and pose a potential health risk to residents, particularly preschool children, in Bangkok.
本研究旨在测定泰国曼谷 99 户家庭的室内灰尘中所摄入邻苯二甲酸酯的浓度，并评估人体接触此类物质的情况。研究人员使用手持吸尘器采集灰尘样本，然后采用气相色谱-质谱联用仪进行分析，结果显示灰尘中邻苯二甲酸酯的平均含量为 3477µg/g，范围为 753-13810µg/g，其中含量最高的是邻苯二甲酸二（2-乙基）己酯（DEHP，中位数为 1739µg/g，范围为 467-8172µg/g），其次是邻苯二甲酸二异壬酯（DiNP，中位数为 611µg/g，范围为 15.2-11052µg/g）。多户公寓（公寓内有聚氯乙烯 [PVC] 地板材料）、多户公寓（公寓内无 PVC 地板材料）和单户住宅（住宅内无 PVC 地板材料）室内灰尘中的 DEHP 中位数及范围分别为 3009µg/g 和 568-6898µg/g、1479µg/g 和 467-8172µg/g、1207µg/g 和 611-3518µg/g。在高浓度室内灰尘中，居住于这三种类型住宅中的学龄前儿童接触的 DEHP 水平均超过了美国环保署的参考剂量（20µg/g）。研究结果表明，含有邻苯二甲酸酯的家用产品可能是室内环境中邻苯二甲酸酯的主要来源之一，这对曼谷居民，尤其是学龄前儿童的健康构成了潜在威胁。
