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透析和肾移植患者的抑郁与焦虑:一项横断面研究。

Depression and anxiety among patients undergoing dialysis and kidney transplantation: a cross-sectional study.

作者信息

Brito Daniela Cristina Sampaio de, Machado Elaine Leandro, Reis Ilka Afonso, Carmo Lilian Pires de Freitas do, Cherchiglia Mariangela Leal

机构信息

MSc. Psychologist and Doctoral Student, Research Group on Economy and Health, Department of Preventive and Social Medicine, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte (MG), Brazil.

MD, PhD. Psychologist and Professor, Department of Preventive and Social Medicine, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte (MG); and Researcher, Research Group on Economy and Health, Department of Preventive and Social Medicine, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte (MG), Brazil.

出版信息

Sao Paulo Med J. 2019 Jul 15;137(2):137-147. doi: 10.1590/1516-3180.2018.0272280119.

DOI:10.1590/1516-3180.2018.0272280119
PMID:31314874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9721231/
Abstract

BACKGROUND

Depression and anxiety are the most prevalent psychological disorders among end-stage renal disease patients and are associated with various conditions that result in poorer health outcomes, e.g. reduced quality of life and survival. We aimed to investigate the prevalences of depression and anxiety among patients undergoing renal replacement therapy.

DESIGN AND SETTING

Cross-sectional study in Belo Horizonte, Brazil.

METHODS

Patients' depression and anxiety levels were assessed using the Beck Inventory. The independent variables were the 36-Item Short-Form Health Survey (SF-36), Charlson Comorbidity Index and Global Subjective Assessment, along with sociodemographic and clinical characteristics.

RESULTS

205 patients were included. Depression and anxiety symptoms were detected in 41.7% and 32.3% of dialysis patients and 13.3% and 20.3% of transplantation patients, respectively. Lower SF-36 mental summary scores were associated with depression among transplantation patients (odds ratio, OR: 0.923; 95% confidence interval, CI: 0.85-0.99; P = 0.03) and dialysis patients (OR: 0.882; 95% CI: 0.83-0.93; P ≤ 0.001). Physical component summary was associated with depression among dialysis patients (OR: 0.906; 95% CI: 0.85-0.96; P = 0.001). Loss of vascular access (OR: 3.672; 95% CI: 1.05-12.78; P = 0.04), comorbidities (OR: 1.578; 95% CI: 1.09-2.27; P = 0.01) and poorer SF-36 mental (OR: 0.928; 95% CI: 0.88-0.97; P = 0.002) and physical (OR: 0.943; 95% CI: 0.89-0.99; P = 0.03) summary scores were associated with anxiety among -dialysis patients.

CONCLUSIONS

Depression and anxiety symptoms occurred more frequently among patients undergoing dialysis. Quality of life, comorbidities and loss of vascular access were associated factors.

摘要

背景

抑郁和焦虑是终末期肾病患者中最常见的心理障碍,与导致健康状况较差的各种情况相关,例如生活质量下降和生存率降低。我们旨在调查接受肾脏替代治疗的患者中抑郁和焦虑的患病率。

设计与地点

巴西贝洛奥里藏特的横断面研究。

方法

使用贝克量表评估患者的抑郁和焦虑水平。自变量包括36项简短健康调查问卷(SF - 36)、查尔森合并症指数和整体主观评估,以及社会人口统计学和临床特征。

结果

纳入205例患者。透析患者中分别有41.7%和32.3%检测出抑郁和焦虑症状,移植患者中分别为13.3%和20.3%。较低的SF - 36心理综合评分与移植患者(比值比,OR:0.923;95%置信区间,CI:0.85 - 0.99;P = 0.03)和透析患者(OR:0.882;95% CI:0.83 - 0.93;P≤0.001)的抑郁相关。身体综合评分与透析患者的抑郁相关(OR:0.906;95% CI:0.85 - 0.96;P = 0.001)。血管通路丧失(OR:3.672;95% CI:1.05 - 12.78;P = 0.04)、合并症(OR:1.578;95% CI:1.09 - 2.27;P = 0.01)以及较差的SF - 36心理(OR:0.928;95% CI:0.88 - 0.97;P = 0.002)和身体(OR:0.943;95% CI:0.89 - 0.99;P = 0.03)综合评分与透析患者的焦虑相关。

结论

透析患者中抑郁和焦虑症状更为常见。生活质量、合并症和血管通路丧失是相关因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f508/9721231/0b754f2b027f/1806-9460-spmj-137-02-137-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f508/9721231/0b754f2b027f/1806-9460-spmj-137-02-137-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f508/9721231/0b754f2b027f/1806-9460-spmj-137-02-137-gf1.jpg

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