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淋巴细胞在急性和慢性肝炎中形成稳定的E花环。

Lymphocytes forming stable E-rosettes in acute and chronic hepatitis.

作者信息

Wansbrough-Jones M H, Scullard G H, Nicholson A, Eddleston A L, Williams R

出版信息

Clin Exp Immunol. 1979 Mar;35(3):390-6.

Abstract

Lymphocytes forming E-rosettes with sheep erythrocytes which do not disintegrate at 37 degrees C have been demonstrated in increased numbers in peripheral blood of patients with acute type B hepatitis (6--20% of lymphocytes) and with HBsAg negative active chronic hepatitis (9--28% of lymphocytes). They were not increased in patients with HBsAg positive active chronic hepatitis. Such lymphocytes were adherent to nylon wool and a large proportion of them had FcIgG receptors (21--69%). These are properties of a subpopulation of T lymphocytes having suppressor function.

摘要

在37℃下不发生溶解的、能与绵羊红细胞形成E花环的淋巴细胞,在急性B型肝炎患者(占淋巴细胞的6%-20%)和HBsAg阴性的活动性慢性肝炎患者(占淋巴细胞的9%-28%)的外周血中数量增多。而在HBsAg阳性的活动性慢性肝炎患者中,这类细胞未增多。这些淋巴细胞能黏附于尼龙棉,其中很大一部分具有FcIgG受体(21%-69%)。这些是具有抑制功能的T淋巴细胞亚群的特性。

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