Colombo M, Vernace S J, Paronetto F
Clin Exp Immunol. 1977 Oct;30(1):4-9.
Absolute numbers of T and B lymphocytes as well as active E rosette-forming cells were measured in twenty-seven patients with chronic active hepatitis (CAH), and in thirty control patients. In patients with CAH without cirrhosis, active E rosette-forming cells (a subpopulation of T lymphocytes considered to be actively involved in cell-mediated immune reactions) as well as lymphocytes with surface markers for IgA, IgM and IgG were increased. In patients with CAH and cirrhosis, total T lymphocytes were decreased. These results emphasize the significance of lymphocytes in CAH, and suggest the importance of monitoring T- and B-cell populations in patients with this disease.
对27例慢性活动性肝炎（CAH）患者和30例对照患者的T淋巴细胞、B淋巴细胞的绝对数量以及活性E玫瑰花结形成细胞进行了检测。在无肝硬化的CAH患者中，活性E玫瑰花结形成细胞（被认为积极参与细胞介导免疫反应的T淋巴细胞亚群）以及具有IgA、IgM和IgG表面标志物的淋巴细胞数量增加。在患有CAH和肝硬化的患者中，总T淋巴细胞数量减少。这些结果强调了淋巴细胞在CAH中的重要性，并表明监测该疾病患者的T细胞和B细胞群体的重要性。
