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全谷物和谷物纤维摄入量与2型糖尿病风险:一项荟萃分析。

Whole grain and cereal fiber intake and the risk of type 2 diabetes: a meta-analysis.

作者信息

Wang Yanqiu, Duan Ying, Zhu Lijun, Fang Zhengmei, He Lianping, Ai Dong, Jin Yuelong

机构信息

Department Epidemiology and Biostatistics, School of Public Health, Wannan Medical College Wuhu 241002, Anhui, China.

Hospital Infection Management Office, The Second People's Hospital of Hefei Hefei 230011, Anhui, China.

出版信息

Int J Mol Epidemiol Genet. 2019 Jun 15;10(3):38-46. eCollection 2019.

Abstract

In recent years, cardiovascular diseases (CVDs) have become a focus topic and global concern. There have been mixed reports on the relationship between whole grain or cereal fiber intake and the risk of type 2 diabetes. To evaluate whole grain or cereal intake on the risk of type 2 diabetes, we collected related literature on the relationship between whole grain or cereal fiber intake and the risk of type 2 diabetes. Eligible studies were identified from PubMed, Web of Science, and EBSCO (from 2007 to 2015). A total of three studies on whole grains were included, three studies about cereal fiber, and two on both whole grains and cereal fiber. We calculated the summary relative risks (RRs) using the random effects model. Eight studies contained 14,728 type 2 diabetes cases out of 434,903 subjects. Whole grain or cereal fiber intake is associated with type 2 diabetes (the overall RR was 0.68; 95% CI was 0.64-0.73) with significant heterogeneity in study-specific estimates ( =0%, =0.452). Whole grain and cereal fiber intake are inversely associated with the risk of type 2 diabetes.

摘要

近年来,心血管疾病(CVDs)已成为一个重点话题和全球关注的问题。关于全谷物或谷物纤维摄入量与2型糖尿病风险之间的关系,一直存在不同的报道。为了评估全谷物或谷物摄入量对2型糖尿病风险的影响,我们收集了有关全谷物或谷物纤维摄入量与2型糖尿病风险之间关系的相关文献。从PubMed、科学网和EBSCO(2007年至2015年)中确定符合条件的研究。总共纳入了三项关于全谷物的研究、三项关于谷物纤维的研究以及两项关于全谷物和谷物纤维的研究。我们使用随机效应模型计算汇总相对风险(RRs)。八项研究在434,903名受试者中包含14,728例2型糖尿病病例。全谷物或谷物纤维摄入量与2型糖尿病相关(总体RR为0.68;95%CI为0.64 - 0.73),各研究特定估计值存在显著异质性(I² = 0%,P = 0.452)。全谷物和谷物纤维摄入量与2型糖尿病风险呈负相关。

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