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石器时代饮食对慢性病人体测量标志物的影响:系统评价和荟萃分析。

Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis.

机构信息

Postgraduate Program in Colletive Health, Universidade Estadual do Ceará (UECE), Fortaleza, Brazil.

Nutrition course, Universidade de Fortaleza (UNIFOR), Fortaleza, Brazil.

出版信息

Nutr J. 2019 Jul 23;18(1):41. doi: 10.1186/s12937-019-0457-z.

DOI:10.1186/s12937-019-0457-z
PMID:31337389
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6647066/
Abstract

BACKGROUND

The Paleolithic diet has been studied in the scope of prevention and control of chronic noncommunicable diseases (CNCD). The objective of this study was to analyze the influence of the Paleolithic diet on the prevention and control of CNCD in humans, specifically on anthropometric markers, through a systematic review with meta-analysis.

METHODS

What is the effect of the Paleolithic diet on anthropometric parameters (weight, body mass index and waist circumference) compared to other control diets based on recommendations in adults? We included only randomized studies with humans that used the Paleolithic Diet in the prevention and control of CNCD published in Portuguese, English or Spanish. The search period was until March 2019, in the LILACS, PubMed, Scielo, Science Direct, Medline, Web of Science and Scopus databases. The abstracts were evaluated by two researchers. We found 1224 articles, of which 24 were selected and 11 were included in the meta-analysis. The effect of dietary use on body weight, body mass index and waist circumference was evaluated.

RESULTS

The summary of the effect showed a loss of - 3.52 kg in the mean weight (CI 95%: - 5.26; - 1.79; p < 0,001; I = 24%) of people who adopted the Paleolithic diet compared to diets based on recommendations. The analysis showed a positive association of adopting the Paleolithic diet in relation to weight loss. The effect was significant on weight, body mass index and waist circumference.

CONCLUSION

The Paleolithic diet may assist in controlling weight and waist circumference and in the management of chronic diseases. However, more randomized clinical studies with larger populations and duration are necessary to prove health benefits.

TRIAL REGISTRATION

CRD42015027849 .

摘要

背景

石器时代饮食法在预防和控制慢性非传染性疾病(CNCD)方面已得到研究。本研究的目的是通过系统评价和荟萃分析,分析石器时代饮食法对人类预防和控制 CNCD 的影响,特别是对人体测量指标的影响。

方法

与基于建议的其他对照饮食相比,石器时代饮食对人体测量参数(体重、体重指数和腰围)的影响如何?我们仅纳入了使用石器时代饮食法预防和控制 CNCD 的随机对照研究,这些研究使用的是人类,并发表在葡萄牙语、英语或西班牙语中。检索时间截至 2019 年 3 月,检索数据库包括 LILACS、PubMed、Scielo、Science Direct、Medline、Web of Science 和 Scopus。摘要由两位研究人员进行评估。我们共发现了 1224 篇文章,其中有 24 篇被评估,11 篇被纳入荟萃分析。饮食使用对体重、体重指数和腰围的影响进行了评估。

结果

汇总效应显示,与基于建议的饮食相比,采用石器时代饮食的人的平均体重减轻了-3.52kg(95%CI:-5.26;-1.79;p<0.001;I=24%)。分析表明,采用石器时代饮食与体重减轻之间存在正相关关系。该效应在体重、体重指数和腰围方面均具有统计学意义。

结论

石器时代饮食可能有助于控制体重和腰围,并有助于管理慢性疾病。然而,需要更多的、更大规模的、持续时间更长的随机临床试验来证明其对健康的益处。

试验注册

CRD42015027849。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/1f686e3a1793/12937_2019_457_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/6cc36cf08914/12937_2019_457_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/9646a78956a9/12937_2019_457_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/1974c975b5cd/12937_2019_457_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/1f686e3a1793/12937_2019_457_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/6cc36cf08914/12937_2019_457_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/9646a78956a9/12937_2019_457_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/1974c975b5cd/12937_2019_457_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd0a/6647066/1f686e3a1793/12937_2019_457_Fig4_HTML.jpg

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