Song Yanping, Cui Xueling, Zhang Yan, Gao Huiying, Cai Qiaoying, Mu Zhenzhen
Department of Geriatric Health Care and Management, Heze Medical College.
Department of Breast and Thyroid Surgery, Heze Municipal Hospital.
J Nerv Ment Dis. 2019 Aug;207(8):693-699. doi: 10.1097/NMD.0000000000001032.
Postoperative cognitive dysfunction is a severe outcome after lung transplantation, especially in the elderly lung transplant recipients. Home-based computerized cognitive training (CCT) is a widely used intervention for cognition improvement, but its efficacy has not been validated in this population. A randomized controlled trial was conducted to analyze the effect of CCT on elderly lung transplant recipients. The participants received either an 8-week CCT intervention or usual care. The changes of cognitive function were assessed between preintervention (T1), postintervention (T2), and 12 weeks postintervention (T3). Among the 46 participants, 91.3% completed the interventions. The CCT group performed better than the control group on Digit-Span Forward Test (T3: p = 0.0044) and Verbal Fluency Test (T3: p = 0.0331), indicating the efficacy of CCT on verbal memory in the elderly lung transplant recipients. Although varied impacts were observed on different cognitive domains, it seems promising to use CCT on the elderly population after lung transplantation.
术后认知功能障碍是肺移植后的严重后果，尤其在老年肺移植受者中。基于家庭的计算机化认知训练（CCT）是一种广泛用于改善认知的干预措施，但其疗效尚未在该人群中得到验证。进行了一项随机对照试验，以分析CCT对老年肺移植受者的影响。参与者接受了为期8周的CCT干预或常规护理。在干预前（T1）、干预后（T2）和干预后12周（T3）评估认知功能的变化。在46名参与者中，91.3%完成了干预。CCT组在数字广度顺背测验（T3：p = 0.0044）和言语流畅性测验（T3：p = 0.0331）上的表现优于对照组，表明CCT对老年肺移植受者的言语记忆有效。尽管在不同认知领域观察到了不同的影响，但在老年肺移植后人群中使用CCT似乎很有前景。
