Aryan Arvin, Alaeen Hurieh, Dadgostar Mehrdad, Rostamian Abdorrahman, Ghajarzadeh Mahsa
Advanced Diagnostic and Interventional Radiology Research Center, Imam Khomeini Hospital, Tehran Iran.
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Int J Prev Med. 2019 Jun 7;10:91. doi: 10.4103/ijpvm.IJPVM_43_18. eCollection 2019.
The objective of the study is to evaluate elastography ultrasound findings in patients with scleroderma (SS) and to clarify the effectiveness of elastosonography to differentiate scleroderma lesions from any skin lesion considering tissue elasticity.
Thirty-six SS patients definite diagnosis of systemic sclerosis according to American College of Rheumatology criteria and 36 healthy subjects were enrolled. Volar aspect of the middle forearm and arm in addition to the dorsal aspect of the fingers were evaluated by sonoelastography. The RGB (red, green, blue) image is a three-dimensional matrix. A color image RGB is an M × N × 3 array of color pixels. The total pixels, total blue pixels, and blue index compared between SS cases and controls.
Mean age of patients was 41.3 ± 10.3 years and mean age of controls was 39.8 ± 9.3 years. Mean-modified Rodnan skin score of the whole body was 11.9 and mean duration of disease was 6.2 years. Mean total blue pixels in the arm were significantly different between cases and controls. Mean total image pixels, total blue pixels, and blue index in the forearm were significantly different between cases and controls. Elastography findings in the finger were not significantly different between cases and controls.
Sonoelastography could be used for evaluating skin of forearm in sclerodermic cases which will be helpful for disease evaluation in clinical course.
本研究的目的是评估硬皮病（SS）患者的弹性成像超声表现，并根据组织弹性阐明弹性超声在鉴别硬皮病病变与其他皮肤病变方面的有效性。
纳入36例根据美国风湿病学会标准确诊为系统性硬化症的SS患者和36名健康受试者。通过超声弹性成像评估前臂中部和手臂的掌侧以及手指的背侧。RGB（红、绿、蓝）图像是一个三维矩阵。彩色图像RGB是一个M×N×3的彩色像素阵列。比较SS病例和对照组之间的总像素、总蓝色像素和蓝色指数。
患者的平均年龄为41.3±10.3岁，对照组的平均年龄为39.8±9.3岁。全身平均改良Rodnan皮肤评分为11.9，平均病程为6.2年。病例组和对照组手臂的平均总蓝色像素有显著差异。病例组和对照组前臂的平均总图像像素、总蓝色像素和蓝色指数有显著差异。病例组和对照组手指的弹性成像表现无显著差异。
超声弹性成像可用于评估硬皮病患者的前臂皮肤，这将有助于临床病程中的疾病评估。
