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慢性阻塞性肺疾病计算机化分析中的深度学习

Deep Learning on Computerized Analysis of Chronic Obstructive Pulmonary Disease.

作者信息

Altan Gokhan, Kutlu Yakup, Allahverdi Novruz

出版信息

IEEE J Biomed Health Inform. 2019 Jul 26. doi: 10.1109/JBHI.2019.2931395.

DOI:10.1109/JBHI.2019.2931395
PMID:31369388
Abstract

GOAL

Chronic obstructive pulmonary disease (COPD) is one of the deadliest diseases in the world. Because COPD is an incurable disease and requires considerable time to be diagnosed even by an experienced specialist, it becomes important to provide analysis abnormalities in simple ways. The aim of the study is comparing multiple machine learning algorithms for the early diagnosis of COPD using multi-channel lung sounds.

METHODS

Deep learning is an efficient machine-learning algorithm, which comprises unsupervised training to reduce optimization and supervised training by a feature-based distribution of classification parameters. This study focuses on analyzing multichannel lung sounds using statistical features of frequency modulations that are extracted using the Hilbert-Huang transform.

RESULTS

Deep learning algorithm was used in the classification stage of the proposed model to separate the patients with COPD and healthy subjects. The proposed DL model with the Hilbert-Huang transform based statistical features was successful in achieving high classification performance rates of 93.67%, 91%, and 96.33% for accuracy, sensitivity, and specificity, respectively.

CONCLUSION

The proposed computerized analysis of the multi-channel lung sounds using DL algorithms provides a standardized assessment with high classification performance.

SIGNIFICANCE

Our study is a pioneer study that directly focuses on the lung sounds to separate COPD and non-COPD patients. Analyzing 12-channel lung sounds gives the advantages of assessing the entire lung obstructions.

摘要

目标

慢性阻塞性肺疾病(COPD)是世界上最致命的疾病之一。由于COPD是一种无法治愈的疾病,即使由经验丰富的专家进行诊断也需要相当长的时间,因此以简单的方式提供分析异常情况变得很重要。本研究的目的是比较多种机器学习算法,利用多通道肺音对COPD进行早期诊断。

方法

深度学习是一种高效的机器学习算法,它包括用于减少优化的无监督训练和通过基于特征的分类参数分布进行的监督训练。本研究重点利用希尔伯特-黄变换提取的频率调制统计特征来分析多通道肺音。

结果

在提出的模型的分类阶段使用深度学习算法来区分COPD患者和健康受试者。所提出的基于希尔伯特-黄变换统计特征的深度学习模型分别在准确率、灵敏度和特异性方面成功实现了93.67%、91%和96.33%的高分类性能率。

结论

所提出的使用深度学习算法对多通道肺音进行计算机化分析提供了具有高分类性能的标准化评估。

意义

我们的研究是一项开创性研究,直接关注肺音以区分COPD和非COPD患者。分析12通道肺音具有评估整个肺部阻塞情况的优势。

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