Hof H, Hefner P
Institute of Hygiene and Microbiology, University of Würzburg.
Infection. 1988;16 Suppl 2:S141-4. doi: 10.1007/BF01639737.
In different mouse models the pathogenicity of various strains of Listeria monocytogenes and of other Listeria spp. was evaluated. Although quantitative differences of virulence among strains of L. monocytogenes are found, all isolates have to be regarded pathogenic unless essential virulence factors, such as protein composition of the cell wall or hemolysin production, are lacking. Besides L. monocytogenes, only Listeria ivanovii is able to multiply in the murine host, though definitely to a lesser extent. The other Listeria spp., such as Listeria innocua, Listeria welshimeri and Listeria seeligeri, have to be regarded as non-pathogenic.
在不同的小鼠模型中，对各种单核细胞增生李斯特菌菌株以及其他李斯特菌属细菌的致病性进行了评估。尽管发现单核细胞增生李斯特菌菌株之间存在毒力的定量差异，但除非缺乏诸如细胞壁蛋白质组成或溶血素产生等必需的毒力因子，否则所有分离株都应被视为具有致病性。除了单核细胞增生李斯特菌外，只有伊氏李斯特菌能够在小鼠宿主体内繁殖，不过繁殖程度肯定较低。其他李斯特菌属细菌，如无害李斯特菌、威氏李斯特菌和斯氏李斯特菌，则被视为非致病性细菌。
