2018年埃塞俄比亚西北部费莱盖希沃特转诊医院产前门诊孕妇中与乙型肝炎病毒感染相关的危险因素：一项基于机构的横断面研究
Risk factors associated with hepatitis B virus infection among pregnant women attending antenatal clinic at Felegehiwot referral hospital, Northwest Ethiopia, 2018: an institution based cross sectional study.
作者信息
Gedefaw Getnet, Waltengus Fikadu, Akililu Almaz, Gelaye Kihinetu
机构信息
Department of Midwifery, College of Health Sciences, Woldia University, Woldia, Ethiopia.
Department of Midwifery, College of Medicine and Health Sciences, Bahirdar University, Bahirdar, Ethiopia.
出版信息
BMC Res Notes. 2019 Aug 15;12(1):509. doi: 10.1186/s13104-019-4561-0.
Abstract
OBJECTIVE
This study aimed to determine the magnitude of serum HBsAg and the risk factors for hepatitis B virus infection among pregnant women in Bahir Dar. An institution based cross sectional study was implemented from February 1 to May 1, 2018 among 338 pregnant women attending antenatal care clinic at Felegehiwot referral hospital, Bahir Dar, 2018. Systematic random sampling technique was implemented. Blood sample was taken from 338 study participants and serum was tested for hepatitis B surface antigen (HBsAg) using Enzyme Linked ImmunoSorbent Assay.
RESULTS
The overall prevalence of hepatitis B virus infection among pregnant women were 16 (4.7%) (95% CI 2.7, 7.7). Having a history of blood transfusion (AOR = 5.2; 95% CI 1.2-22.3), having a history of multiple sexual partners (AOR = 4.6; 95% CI 1.1-19.6) and having a history tonsillectomy (traditional surgical procedure) (AOR = 3.4; 95% CI 1.1-10.1) were the significant risk factors for hepatitis B virus infection.
摘要
目的
本研究旨在确定巴希尔达孕妇血清乙肝表面抗原（HBsAg）的水平以及乙肝病毒感染的危险因素。2018年2月1日至5月1日，在巴希尔达费莱格希沃特转诊医院对338名参加产前检查门诊的孕妇开展了一项基于机构的横断面研究。采用系统随机抽样技术。采集了338名研究参与者的血样，并使用酶联免疫吸附测定法检测血清中的乙肝表面抗原（HBsAg）。
结果
孕妇中乙肝病毒感染的总体患病率为16例（4.7%）（95%置信区间2.7, 7.7）。有输血史（调整后比值比[AOR]=5.2；95%置信区间1.2 - 22.3）、有多个性伴侣史（AOR = 4.6；95%置信区间1.1 - 19.6）以及有扁桃体切除术史（传统外科手术）（AOR = 3.4；95%置信区间1.1 - 10.1）是乙肝病毒感染的显著危险因素。
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