Panayotov Valentin Stefanov
National Sports Academy, Sofia, Bulgaria.
Front Psychiatry. 2019 Jul 30;10:550. doi: 10.3389/fpsyt.2019.00550. eCollection 2019.
In recent years the prevalence of obesity in developed countries has increased to the point that some authorities have coined the term "obesity epidemics." Combining energy intake control measures (via diet) with protocols for increasing energy expenditure (predominantly low to medium intensity aerobic exercise) proved to be the most effective approach in addressing this problem. In this experiment, we studied for a possible placebo effect of a weight loss program on changes in body mass and fat tissue in overweight or obese people. Fourteen healthy adults of both sexes aged between 19 and 45 with body mass index (BMI) > 27 participated in the study. They were randomly assigned to two groups-one experimental and one control. The subjects in the experimental group followed an isocaloric diet but were told they were put on a calorie-deficient regimen. The subjects in the control group were aware they followed an energy-balanced diet. All participants were engaged in regular sessions of resistance exercise three times a week with total energy cost of approximately 750-900 kcal/week. We studied within-group differences of body mass, percentage of fat tissue, and BMI. All three variables reduced in value in the experimental group: body mass-9.25 ± 5.26 kg, percentage of fat tissue-3.4 ± 0.97%, and BMI-2.88 ± 1.50. No statistically significant within-group differences were measured in the control group. Despite some methodological biases of the study construct, in our opinion, a placebo effect could partially explain the changes in the experimental group.
近年来，发达国家肥胖症的患病率已上升到一定程度，以至于一些权威机构创造了“肥胖流行”这一术语。事实证明，将能量摄入控制措施（通过饮食）与增加能量消耗的方案（主要是低至中等强度的有氧运动）相结合是解决这一问题的最有效方法。在本实验中，我们研究了减肥计划对超重或肥胖人群体重和脂肪组织变化可能产生的安慰剂效应。14名年龄在19至45岁之间、体重指数（BMI）>27的健康成年男女参与了该研究。他们被随机分为两组，一组为实验组，一组为对照组。实验组的受试者遵循等热量饮食，但被告知他们采用的是热量不足的饮食方案。对照组的受试者知道自己遵循的是能量平衡饮食。所有参与者每周进行三次常规抗阻运动，每周总能量消耗约为750 - 900千卡。我们研究了体重、脂肪组织百分比和BMI的组内差异。实验组的这三个变量值均有所下降：体重下降了9.25±5.26千克，脂肪组织百分比下降了3.4±0.97%，BMI下降了2.88±1.50。对照组未测得具有统计学意义的组内差异。尽管该研究结构存在一些方法上的偏差，但我们认为，安慰剂效应可以部分解释实验组的变化。
