Al-Duais Mohammed A, Al-Awthan Yahya S
Department of Biochemistry, Faculty of Science, University of Tabuk, Tabuk, KSA.
Department of Biology, Faculty of Science, Ibb University, Ibb, Yemen.
J Taibah Univ Med Sci. 2019 Jan 30;14(2):163-171. doi: 10.1016/j.jtumed.2018.12.003. eCollection 2019 Apr.
To estimate the prevalence of dyslipidemia and patterns of lipid profile and associated factors among Yemeni university students.
This cross-sectional study included 240 Yemeni students (116 males and 124 females) at Ibb University. The students were randomly selected from various faculties of the university. Demographic and clinical data were obtained from all participants. Fasting blood specimens were collected from all students for measurement of serum levels of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). The criteria of the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) were used.
The mean age of the studied cohort was 19.8 ± 1.8 years; 48.3% were men and 51.7% were women. About 56.7% of the participants were from rural areas. Qat chewers and cigarette smokers comprised 63.3% and 6.7% of the cohort, respectively. No obese students were found in this study; however, 11.7% were overweight. The overall prevalence of dyslipidemia, hypercholesterolemia, hypertriglyceridemia, high LDL-C, and low HDL-C among the participating students were 86.7%, 21.7%, 23.8%, 31.7%, and 81.7%, respectively. Mixed hyperlipidemia was present in 8.8% of the students. The prevalence of isolated hypercholesterolemia, hypertriglyceridemia, and low HDL-C was 12.9%, 15%, and 70%, respectively. Dyslipidemia was significantly associated with male sex, increasing age, urban residence, and medical and natural science faculties. In contrast, smoking, qat chewing, physical activity, and the consumption of fast food, fruits and vegetables, and fish were not significantly associated with dyslipidemia.
To our knowledge, this is the first human study conducted at Ibb University during wartime in Yemen. Dyslipidemia was highly prevalent among healthy Yemeni university students in Ibb city. Low HDL-C was the most prevalent type of dyslipidemia, followed by increased levels of LDL-C. Gender, age, residence, and type of faculty were also closely related to dyslipidemia. These results indicate the need for specialized programs to determine blood lipid levels and initiate intervention programs to reduce the prevalence and prevent the complications of dyslipidemia among Yemeni university students.
评估也门大学生血脂异常的患病率、血脂谱模式及相关因素。
这项横断面研究纳入了伊卜大学的240名也门学生(116名男性和124名女性)。这些学生是从该大学的各个学院中随机选取的。收集了所有参与者的人口统计学和临床数据。采集了所有学生的空腹血标本,用于检测血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平。采用了美国国家胆固醇教育计划成人治疗组第三次报告(NCEP-ATP III)的标准。
研究队列的平均年龄为19.8±1.8岁;48.3%为男性,51.7%为女性。约56.7%的参与者来自农村地区。嚼卡特叶者和吸烟者分别占队列的63.3%和6.7%。本研究中未发现肥胖学生;然而,11.7%的学生超重。参与研究的学生中血脂异常、高胆固醇血症、高甘油三酯血症、高LDL-C和低HDL-C的总体患病率分别为86.7%、21.7%、23.8%、31.7%和81.7%。8.8%的学生存在混合型高脂血症。单纯高胆固醇血症、高甘油三酯血症和低HDL-C的患病率分别为12.9%、15%和70%。血脂异常与男性、年龄增长、城市居住以及医学和自然科学学院显著相关。相比之下,吸烟、嚼卡特叶、体育活动以及快餐、水果、蔬菜和鱼类的消费与血脂异常无显著关联。
据我们所知,这是也门战时在伊卜大学进行的第一项人体研究。血脂异常在伊卜市健康的也门大学生中非常普遍。低HDL-C是最常见的血脂异常类型,其次是LDL-C水平升高。性别、年龄、居住地点和学院类型也与血脂异常密切相关。这些结果表明需要制定专门的项目来测定血脂水平,并启动干预项目以降低也门大学生血脂异常的患病率并预防其并发症。