Kaggie Joshua D, Sapkota Nabraj, Thapa Bijaya, Jeong Kyle, Shi Xianfeng, Morrell Glen, Bangerter Neal K, Jeong Eun-Kee
Department of Radiology and Utah Center for Advanced Imaging Research, University of Utah, Salt Lake City, UT, USA.
Department of Physics, University of Utah, Salt Lake City, UT, USA.
Concepts Magn Reson Part B Magn Reson Eng. 2016 Oct;46B(4):191-201. doi: 10.1002/cmr.b.21347. Epub 2017 Feb 3.
The purpose of this work was to synchronously acquire proton (1H) and sodium (23Na) image data on a 3T clinical MRI system within the same sequence, without internal modification of the clinical hardware, and to demonstrate synchronous acquisition with 1H/23Na-GRE imaging with Cartesian and radial k-space sampling. Synchronous dual-nuclear imaging was implemented by: mixing down the 1H signal so that both the 23Na and 1H signal were acquired at 23Na frequency by the conventional MRI system; interleaving 1H/23Na transmit pulses in both Cartesian and radial sequences; and using phase stabilization on the 1H signal to remove mixing effects. The synchronous 1H/23Na setup obtained images in half the time necessary to sequentially acquire the same 1H and 23Na images with the given setup and parameters. Dual-nuclear hardware and sequence modifications were used to acquire 23Na images within the same sequence as 1H images, without increases to the 1H acquisition time. This work demonstrates a viable technique to acquire 23Na image data without increasing 1H acquisition time using minor additional custom hardware, without requiring modification of a commercial scanner with multinuclear capability.
这项工作的目的是在3T临床MRI系统上,在同一序列内同步采集质子(1H)和钠(23Na)图像数据,而无需对临床硬件进行内部修改,并展示使用笛卡尔和径向k空间采样的1H/23Na-GRE成像进行同步采集。同步双核成像通过以下方式实现:下变频1H信号,以便传统MRI系统在23Na频率下采集23Na和1H信号;在笛卡尔和径向序列中交错1H/23Na发射脉冲;对1H信号使用相位稳定来消除混频效应。与给定设置和参数下顺序采集相同的1H和23Na图像所需时间相比,同步1H/23Na设置获得图像的时间缩短了一半。使用双核硬件和序列修改在与1H图像相同的序列内采集23Na图像,而不增加1H采集时间。这项工作展示了一种可行的技术,即使用少量额外的定制硬件来采集23Na图像数据,而不增加1H采集时间,且无需对具有多核能力的商业扫描仪进行修改。