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海洋单细胞微藻甲藻属(Porphyridium spp.)生物活性物质生产的研究进展

Advances in the production of bioactive substances from marine unicellular microalgae Porphyridium spp.

机构信息

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, PR China; Department of Applied Biology, East China University of Science and Technology, Shanghai 200237, PR China.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, PR China; State Key Laboratory of South China Sea Marine Resource Utilization, Hainan University, Haikou 570228, PR China; Department of Applied Biology, East China University of Science and Technology, Shanghai 200237, PR China.

出版信息

Bioresour Technol. 2019 Nov;292:122048. doi: 10.1016/j.biortech.2019.122048. Epub 2019 Aug 22.

Abstract

Porphyridium spp. are a group of unicellular marine microalgae belonging to the Rhodophyta, which evolved over one billion years and are a source of a variety of natural active components. They can naturally and efficiently accumulate phycobilin, sulfated polysaccharides, polyunsaturated fatty acids and other bioactive substances. At present, numerous attempts have been made to explore the species Porphyridium spp., whereas mainly focused on cultivation methods, metabolism regulation and the function and application of bioactive products. There is a lack of systematic summary of the existing research conclusions. In this paper, we summarized the representative results related to culture and metabolism, analyzed and discussed the existing bottleneck restrictions for their large scale application, and proposed the potential industrial development and research direction in the future. This paper is expected to provide reference and thread for research and application of Porphyridium spp..

摘要

紫球藻属(Porphyridium)是红藻门的一类单细胞海洋微藻,在一亿多年前就已经进化,是多种天然活性成分的来源。它们可以自然且高效地积累藻胆蛋白、硫酸多糖、多不饱和脂肪酸和其他生物活性物质。目前,人们已经尝试对紫球藻属(Porphyridium spp.)进行了大量的探索,主要集中在培养方法、代谢调控以及生物活性产物的功能和应用上。然而,对于现有研究结论缺乏系统的总结。本文总结了与培养和代谢相关的代表性研究结果,分析和讨论了其大规模应用所存在的瓶颈限制,并提出了未来潜在的产业发展和研究方向。本文期望为紫球藻属(Porphyridium spp.)的研究和应用提供参考和思路。

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