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用于生物医学的微型/纳米机器人:输送、手术、传感和解毒。

Micro/Nanorobots for Biomedicine: Delivery, Surgery, Sensing, and Detoxification.

机构信息

Department of NanoEngineering, University of California, San Diego, La Jolla, CA 92093, USA.

出版信息

Sci Robot. 2017 Mar 15;2(4). doi: 10.1126/scirobotics.aam6431. Epub 2017 Mar 1.

DOI:10.1126/scirobotics.aam6431
PMID:31552379
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6759331/
Abstract

Micro- and nanoscale robots that can effectively convert diverse energy sources into movement and force represent a rapidly emerging and fascinating robotics research area. Recent advances in the design, fabrication, and operation of micro/nanorobots have greatly enhanced their power, function, and versatility. The new capabilities of these tiny untethered machines indicate immense potential for a variety of biomedical applications. This article reviews recent progress and future perspectives of micro/nanorobots in biomedicine, with a special focus on their potential advantages and applications for directed drug delivery, precision surgery, medical diagnosis and detoxification. Future success of this technology, to be realized through close collaboration between robotics, medical and nanotechnology experts, should have a major impact on disease diagnosis, treatment, and prevention.

摘要

微纳机器人能够有效地将各种能源转化为运动和力,代表了一个迅速崛起的迷人机器人研究领域。微/纳米机器人的设计、制造和操作方面的最新进展极大地增强了它们的动力、功能和多功能性。这些小型无绳机器的新功能表明,它们在各种生物医学应用中具有巨大的潜力。本文综述了微纳机器人在生物医学中的最新进展和未来展望,特别关注它们在靶向药物输送、精准手术、医学诊断和解毒方面的潜在优势和应用。这项技术的未来成功,需要机器人、医学和纳米技术专家之间的紧密合作,将对疾病的诊断、治疗和预防产生重大影响。

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本文引用的文献

1
Robotically controlled microprey to resolve initial attack modes preceding phagocytosis.机器人控制的微猎物,以解析吞噬作用之前的初始攻击模式。
Sci Robot. 2017 Jan 4;2(2). doi: 10.1126/scirobotics.aah6094.
2
Micro- and nano-motors for biomedical applications.用于生物医学应用的微纳马达。
J Mater Chem B. 2014 May 7;2(17):2395-2408. doi: 10.1039/c3tb21451f. Epub 2013 Dec 5.
3
Micromotors Spontaneously Neutralize Gastric Acid for pH-Responsive Payload Release.微型马达自发中和胃酸以实现 pH 响应的药物释放。
Biomimetics (Basel). 2025 Jul 22;10(8):479. doi: 10.3390/biomimetics10080479.
4
Biomimetic magnetobacterial microrobots for active pneumonia therapy.用于活性肺炎治疗的仿生磁细菌微型机器人。
Nat Commun. 2025 Aug 22;16(1):7856. doi: 10.1038/s41467-025-63231-6.
5
Mechanical Agitation-Assisted Transmembrane Drug Delivery by Magnetically Powered Spiky Nanorobots.磁性驱动尖刺纳米机器人辅助的机械搅拌跨膜药物递送
Research (Wash D C). 2025 Aug 13;8:0768. doi: 10.34133/research.0768. eCollection 2025.
6
Recent Advances in Membrane-Coated Micro/Nanomotors in Biological Applications.膜包覆微纳马达在生物应用中的最新进展
Int J Nanomedicine. 2025 Jul 28;20:9427-9446. doi: 10.2147/IJN.S526671. eCollection 2025.
7
Amino acid coating enables micromotor operation in physiological conditions.氨基酸涂层使微电机能够在生理条件下运行。
Proc Natl Acad Sci U S A. 2025 Jul 22;122(29):e2510091122. doi: 10.1073/pnas.2510091122. Epub 2025 Jul 17.
8
Picoeukaryote-based biohybrid microrobots for active delivery in the kidney.用于肾脏主动递送的基于微微型真核生物的生物杂交微型机器人。
Sci Adv. 2025 Jul 11;11(28):eadw8578. doi: 10.1126/sciadv.adw8578.
9
Knowledge mapping of micro/nanomotors in cancer treatment: a bibliometric analysis (2006-2025).癌症治疗中微/纳米马达的知识图谱:文献计量分析(2006 - 2025年)
Discov Oncol. 2025 Jul 5;16(1):1264. doi: 10.1007/s12672-025-03087-w.
10
Femtosecond laser-assisted printing of hard magnetic microrobots for swimming upstream in subcentimeter-per-second blood flow.用于在每秒厘米级血流中逆流游动的硬磁微机器人的飞秒激光辅助打印
Sci Adv. 2025 Jul 4;11(27):eadw1272. doi: 10.1126/sciadv.adw1272.
Angew Chem Int Ed Engl. 2017 Feb 13;56(8):2156-2161. doi: 10.1002/anie.201611774. Epub 2017 Jan 20.
4
Soft Actuators for Small-Scale Robotics.用于小型机器人的软致动器。
Adv Mater. 2017 Apr;29(13). doi: 10.1002/adma.201603483. Epub 2016 Dec 29.
5
Hybrid Magnetoelectric Nanowires for Nanorobotic Applications: Fabrication, Magnetoelectric Coupling, and Magnetically Assisted In Vitro Targeted Drug Delivery.用于纳米机器人应用的混合磁电纳米线:制造、磁电耦合和磁辅助体外靶向药物输送。
Adv Mater. 2017 Feb;29(8). doi: 10.1002/adma.201605458. Epub 2016 Dec 12.
6
Designing Micro- and Nanoswimmers for Specific Applications.为特定应用设计微纳游动器。
Acc Chem Res. 2017 Jan 17;50(1):2-11. doi: 10.1021/acs.accounts.6b00386. Epub 2016 Nov 3.
7
Transient Micromotors That Disappear When No Longer Needed.需要时出现,不需要时消失的瞬态微型马达。
ACS Nano. 2016 Nov 22;10(11):10389-10396. doi: 10.1021/acsnano.6b06256. Epub 2016 Oct 28.
8
Programmable artificial phototactic microswimmer.可编程人工趋光微型游泳者。
Nat Nanotechnol. 2016 Dec;11(12):1087-1092. doi: 10.1038/nnano.2016.187. Epub 2016 Oct 17.
9
Enteric Micromotor Can Selectively Position and Spontaneously Propel in the Gastrointestinal Tract.肠道微型马达可在胃肠道中选择性定位并自发推进。
ACS Nano. 2016 Oct 25;10(10):9536-9542. doi: 10.1021/acsnano.6b04795. Epub 2016 Sep 22.
10
Bioengineered and biohybrid bacteria-based systems for drug delivery.基于生物工程和生物杂交细菌的药物输送系统。
Adv Drug Deliv Rev. 2016 Nov 15;106(Pt A):27-44. doi: 10.1016/j.addr.2016.09.007. Epub 2016 Sep 15.