Department of Agricultural Sciences, West Texas A&M University, WTAMU Box 60998, Canyon, TX 79016, USA.
SciWrite Consulting, PO Box 1041, Canyon, TX 79015, USA.
Vet Clin North Am Food Anim Pract. 2019 Nov;35(3):575-592. doi: 10.1016/j.cvfa.2019.07.003.
Vaccination is a critical component of cattle health management. Effective cattle vaccine programs should consider the timing of vaccination in relation to expected disease challenge, risk for wild-type exposure of various bovine pathogens, and host factors during vaccination. Nearly all consulting veterinarians recommend vaccination of stressed, high-risk calves on feedlot arrival. However, this recommendation fails to consider several factors associated with vaccine efficiency. Further research evaluating vaccine interactions in stressed cattle and potential additive effects of endotoxin from multiple bacterin administration may reveal new evidence-based vaccination guidelines for cattle in the various segments of beef and dairy production systems.
疫苗接种是牛群健康管理的重要组成部分。有效的牛疫苗接种计划应考虑到接种时间与预期疾病挑战、各种牛病原体的野生型暴露风险以及接种时的宿主因素之间的关系。几乎所有的兽医顾问都建议在育肥场到达时给压力大、高风险的小牛接种疫苗。然而，这一建议没有考虑到与疫苗效率相关的几个因素。进一步研究评估应激牛疫苗的相互作用以及多次菌苗接种内毒素的潜在附加效应，可能会为牛肉和奶制品生产系统各个环节的牛提供新的基于证据的疫苗接种指南。
