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高血压患者对疾病、药物治疗及相关药物依从性水平的了解情况。

Knowledge about Disease, Medication Therapy, and Related Medication Adherence Levels among Patients with Hypertension.

作者信息

Gavrilova Anna, Bandere Dace, Rutkovska Ieva, Šmits Dins, Mauriņa Baiba, Poplavska Elita, Urtāne And Inga

机构信息

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Rīga Stradiņš University, LV-1007 Riga, Latvia.

Department of Dosage Form Technology, Faculty of Pharmacy, Rīga Stradiņš University, LV-1007 Riga, Latvia.

出版信息

Medicina (Kaunas). 2019 Oct 28;55(11):715. doi: 10.3390/medicina55110715.

Abstract

A particular problem in cardiology is poor adherence to pharmacological treatment among patients with hypertension. It is known that approximately half of these patients do not use their medications as prescribed by their doctor. Patients may choose not to follow the doctor's recommendations and regularly do not control their blood pressure, owing to many factors. A convenient method for measuring the level of adherence is the Morisky Medication Adherence Scale, which also provides insight into possible remedies for low adherence. We investigated their therapy, knowledge about the disease and its control, and demographic differences to assess the adherence of patients with hypertension. This was a cross-sectional observational study. Data were collected through a survey of 12 pharmacies in Latvia. The study involved 187 participants with hypertension. The prevalence of non-adherence was 46.20% in Latvia. The oldest patients were the most adherent ( = 0.001, β = 0.27). The higher the self-rated extent from 0 to 10, to which the patient takes their antihypertensives exactly as instructed by their physician, the higher the level of adherence ( < 0.0001, β = 0.38), where at "0", the patient does not follow physician instructions at all, and at "10", the patient completely follows the physician's instructions. Non-adherent patients tend to assess their medication-taking behavior more critically than adherent patients. The longer the patient is known to suffer from hypertension, the more adherent he or she is ( = 0.014, β = 0.19). Medication non-adherence among patients with hypertension is high in Latvia. Further investigations are needed to better understand the reasons for this and to establish interventions for improving patient outcomes.

摘要

心脏病学中的一个特殊问题是高血压患者对药物治疗的依从性较差。众所周知,这些患者中约有一半没有按照医生的处方用药。由于多种因素,患者可能会选择不遵循医生的建议,血压也经常得不到控制。一种方便的测量依从性水平的方法是莫利斯基药物依从性量表,它还能为低依从性的可能补救措施提供见解。我们调查了高血压患者的治疗情况、对疾病及其控制的了解以及人口统计学差异,以评估他们的依从性。这是一项横断面观察性研究。数据通过对拉脱维亚12家药店的调查收集。该研究涉及187名高血压患者。拉脱维亚不依从的患病率为46.20%。年龄最大的患者依从性最高( = 0.001,β = 0.27)。患者自我评估从0到10按照医生指示服用降压药的程度越高,依从性水平就越高( < 0.0001,β = 0.38),其中“0”表示患者完全不遵循医生指示,“10”表示患者完全遵循医生指示。不依从的患者往往比依从的患者更批判性地评估自己的用药行为。患者患高血压的时间越长,其依从性就越高( = 0.014,β = 0.19)。拉脱维亚高血压患者的药物不依从率很高。需要进一步调查以更好地理解其原因,并制定改善患者治疗结果的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0961/6915331/3ca3d36bdad2/medicina-55-00715-g001.jpg

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