Zimatkin S M, Ostrovskiĭ Iu M
Biull Eksp Biol Med. 1988 Sep;106(9):283-4.
The histochemical method was used to study the aldehyde dehydrogenase (EC 1.2.1.3.; ALDH) activity in capillaries and glial structures of different regions in the rat central nervous system (CNS). The occurrence of three metabolic barriers for aldehydes on systemic level in the CNS has been shown. They are: the barrier between blood and the nervous tissue (represented by capillary endothelium and surrounding astrocytes ALDH), that between blood and cerebrospinal fluid (ALDH in ependymocytes of vascular plexus), and that between cerebrospinal fluid and nervous tissue (ALDH of ependymocytes covering brain cavities). On the single microregions level a similar barrier is between interstitial fluid and neurons (ALDH of satellite oligodendrocytes).
采用组织化学方法研究大鼠中枢神经系统（CNS）不同区域毛细血管和神经胶质结构中的醛脱氢酶（EC 1.2.1.3.；ALDH）活性。结果表明，在中枢神经系统的全身水平上存在三种醛代谢屏障。它们是：血液与神经组织之间的屏障（由毛细血管内皮和周围星形胶质细胞的ALDH代表）、血液与脑脊液之间的屏障（血管丛室管膜细胞中的ALDH）以及脑脊液与神经组织之间的屏障（覆盖脑腔的室管膜细胞的ALDH）。在单个微区域水平上，类似的屏障存在于组织液与神经元之间（卫星少突胶质细胞的ALDH）。
