来自不同产甲烷菌的甲酰呋喃之间的结构多样性。
Structural diversity among methanofurans from different methanogenic bacteria.
作者信息
White R H
机构信息
Department of Biochemistry and Nutrition, Virginia Polytechnic Institute and State University, Blacksburg 24061.
出版信息
J Bacteriol. 1988 Oct;170(10):4594-7. doi: 10.1128/jb.170.10.4594-4597.1988.
Abstract
An examination of the methanofurans isolated from a wide range of methanogenic bacteria and from Archaeoglobus fulgidus has revealed at least five chromatographically distinct methanofurans. Bacteria from each major genus of methanogenic bacteria have been found to contain a chemically different methanofuran. The nature of the differences in the methanofurans appears to lie in the modification of the side chain attached to the basic core structure of 4-[N-(gamma-L-glutamyl-gamma-L-glutamyl)-p-(beta-aminoethyl)phenoxyme thy l]-2-(amino-methyl)furan. This was supported by the structural elucidation of the methanofuran isolated from Methanobrevibacter smithii, designated methanofuran-c, which was the same as the originally characterized methanofuran except for a hydroxy group at the 2 position of the 4,5-dicarboxyoctanedioic acid moiety of the molecule.
摘要
对从多种产甲烷细菌以及嗜热栖热菌中分离出的甲呋喃进行的研究表明，至少有五种在色谱上不同的甲呋喃。已发现来自每个主要产甲烷细菌属的细菌都含有化学性质不同的甲呋喃。甲呋喃差异的本质似乎在于连接到4-[N-(γ-L-谷氨酰基-γ-L-谷氨酰基)-对-(β-氨基乙基)苯氧基甲基]-2-(氨基甲基)呋喃基本核心结构上的侧链的修饰。从史氏甲烷短杆菌中分离出的甲呋喃（命名为甲呋喃-c）的结构解析支持了这一点，它与最初鉴定的甲呋喃相同，只是分子中4,5-二羧基辛二酸部分的2位有一个羟基。
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本文引用的文献
1
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Science. 1987 May 15;236(4803):822-4. doi: 10.1126/science.236.4803.822.
2
THE COLOUR REACTIONS OF THE HYDROXYSKATOLES.
J Chromatogr. 1965 Feb;17:338-48. doi: 10.1016/s0021-9673(00)99878-9.
3
Propionic acid metabolism. I. The purification and properties of acrylyl coenzme A aminase.
J Biol Chem. 1959 Mar;234(3):490-7.
4
A possible biochemical missing link among archaebacteria.古细菌之间可能存在的生化缺失环节。
Nature. 1987 May 28;327(6120):348-9. doi: 10.1038/327348a0.
5
Metabolism of formate in Methanobacterium formicicum.甲酸甲烷杆菌中甲酸的代谢
J Bacteriol. 1980 Jun;142(3):800-7. doi: 10.1128/jb.142.3.800-807.1980.
6
Rapidly growing rumen methanogenic organism that synthesizes coenzyme M and has a high affinity for formate.快速生长的瘤胃产甲烷微生物，能合成辅酶M，对甲酸具有高亲和力。
Appl Environ Microbiol. 1984 Jul;48(1):81-7. doi: 10.1128/aem.48.1.81-87.1984.
7
8
Evidence of a common pathway of carbon dioxide reduction to methane in methanogens.产甲烷菌中二氧化碳还原为甲烷的共同途径的证据。
J Bacteriol. 1985 Jul;163(1):126-31. doi: 10.1128/jb.163.1.126-131.1985.
9
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