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科罗拉多双胞胎登记处:2019年更新

The Colorado Twin Registry: 2019 Update.

作者信息

Corley Robin P, Reynolds Chandra A, Wadsworth Sally J, Rhea Sally-Ann, Hewitt John K

机构信息

Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.

Department of Psychology, University of California, Riverside, Riverside, CA, USA.

出版信息

Twin Res Hum Genet. 2019 Dec;22(6):707-715. doi: 10.1017/thg.2019.50. Epub 2019 Nov 11.

DOI:10.1017/thg.2019.50
PMID:31708007
Abstract

The Colorado Twin Registry (CTR) is a population-based registry formed from birth and school records including twins born between 1968 and the present. Two previous reports on the CTR [Rhea et al., (2006). Twin Research and Human Genetics, 9, 941-949; Rhea et al., (2013).Twin Research and Human Genetics, 16, 351-357] covered developments in the CTR through 2012. This report briefly summarizes previously presented material on ascertainment and recruitment and the relationships between samples and studies, discusses developments since 2012 for four previously described twin samples, describes two new samples and their complementary studies and expands on two subjects briefly mentioned in the last report: a history of genotyping efforts involving CTR samples, and a survey of collaborations and consortia in which CTR twins have been included. The CTR remains an active resource for both ongoing, longitudinal research and the recruitment of new twin samples for newly identified research opportunities.

摘要

科罗拉多双胞胎登记处(CTR)是一个基于人群的登记处,它由出生记录和学校记录组成,涵盖了1968年至今出生的双胞胎。之前关于CTR的两份报告[Rhea等人,(2006年)。《双胞胎研究与人类遗传学》,9,941 - 949;Rhea等人,(2013年)。《双胞胎研究与人类遗传学》,16,351 - 357]涵盖了截至2012年CTR的发展情况。本报告简要总结了之前关于确定和招募以及样本与研究之间关系的材料,讨论了自2012年以来四个先前描述的双胞胎样本的发展情况,描述了两个新样本及其补充研究,并详细阐述了上一份报告中简要提及的两个主题:涉及CTR样本的基因分型工作历史,以及对包含CTR双胞胎的合作和联盟的调查。CTR仍然是进行中的纵向研究以及为新发现的研究机会招募新的双胞胎样本的活跃资源。

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