Department of Eastern Medicine, Government College University Faisalabad, Faisalabad, Pakistan.
Department of Allied Health Sciences, Sargodha Medical College, University of Sargodha, Sargodha, Pakistan.
J Pharm Pharmacol. 2020 Feb;72(2):161-174. doi: 10.1111/jphp.13185. Epub 2019 Nov 11.
Rosa damascena Mill. is prescribed for the management of chest and abdominal pain, constipation, digestive disorders, menstrual bleeding and liver ailments.
The current review compiles up to date and complete information of whole plant of R. damascena with particular emphasis on its numerous scientifically proved pharmacological effects, traditional and folk medicinal uses.
The data on the pharmacological effects of R. damascena were collected from various databases such as PubMed, Wiley Online Library, Elsevier and Web of Science using the keywords like phytoconstituents, pharmacology, medicinal uses and biological activity of R. damascene. Rosa damascena has a wide spectrum of bio-pharmacological activity like antidepressant, hypoglycaemic, anti-inflammatory, analgesic, antioxidant and antimicrobial. The main ingredients of R. damascena essential oil responsible for pharmacological activity are geraniol and citronellol. Its uses have been widely accepted in traditional system of medicines for the management of numerous diseases of human beings in different dosage forms.
Rosa damascena has a significant place in traditional system of medicine. It is cost-effective and an important plant with curative application in contemporary medicine. Further studies on the characterization of chemical constituents and scientific basis of pharmacological activity of R. damascena should be carried out to evaluate its impact on traditional system of medicines. Large-scale preclinical and clinical trials will be beneficial in investigating the mechanism of the therapeutic potential of R. damascene to explore its uses in pharmaceutical industries.
大马士革玫瑰（Rosa damascena Mill.）被用于治疗胸痛和腹痛、便秘、消化紊乱、月经过多和肝脏疾病。
本综述综合了大马士革玫瑰全株植物的最新和完整信息，特别强调了其众多经过科学证实的药理学作用、传统和民间药用用途。
通过使用“大马士革玫瑰植物成分、药理学、药用用途和生物活性”等关键词，从 PubMed、Wiley Online Library、Elsevier 和 Web of Science 等各种数据库中收集了大马士革玫瑰的药理学作用数据。大马士革玫瑰具有广泛的生物药理学活性，如抗抑郁、降血糖、抗炎、镇痛、抗氧化和抗菌。其主要成分香茅醇和橙花醇负责其药理学活性。其用途已被广泛接受传统医学体系用于管理人类的许多疾病，包括不同的剂型。
大马士革玫瑰在传统医学体系中占有重要地位。它是一种具有成本效益的重要植物，在当代医学中有治疗应用。应进一步开展对大马士革玫瑰化学成分的表征和药理学活性的科学基础的研究，以评估其对传统医学体系的影响。开展大规模的临床前和临床试验将有利于研究其治疗潜力的治疗机制，探索其在制药行业的用途。
