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J Neurosci. 2018 Sep 26;38(39):8407-8420. doi: 10.1523/JNEUROSCI.3458-17.2018. Epub 2018 Aug 27.
2
Predictive validity and correlates of self-assessed resilience among U.S. Army soldiers.美国陆军士兵自我评估韧性的预测效度及其相关性。
Depress Anxiety. 2018 Feb;35(2):122-131. doi: 10.1002/da.22694. Epub 2017 Nov 2.
3
Lifetime Economic Burden of Rape Among U.S. Adults.美国成年人强奸案的终身经济负担。
Am J Prev Med. 2017 Jun;52(6):691-701. doi: 10.1016/j.amepre.2016.11.014. Epub 2017 Jan 30.
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Teleconsent: A Novel Approach to Obtain Informed Consent for Research.远程同意:一种获取研究知情同意的新方法。
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Telemedicine Provides Noninferior Research Informed Consent for Remote Study Enrollment: A Randomized Controlled Trial.远程医疗为远程研究入组提供非劣效性研究知情同意:一项随机对照试验。
Acad Emerg Med. 2016 Jul;23(7):759-65. doi: 10.1111/acem.12966. Epub 2016 Jun 18.
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Testing a machine-learning algorithm to predict the persistence and severity of major depressive disorder from baseline self-reports.测试一种机器学习算法,以根据基线自我报告预测重度抑郁症的持续时间和严重程度。
Mol Psychiatry. 2016 Oct;21(10):1366-71. doi: 10.1038/mp.2015.198. Epub 2016 Jan 5.
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MicroRNA circulating in the early aftermath of motor vehicle collision predict persistent pain development and suggest a role for microRNA in sex-specific pain differences.在机动车碰撞后早期循环的微小RNA可预测持续性疼痛的发展,并提示微小RNA在性别特异性疼痛差异中发挥作用。
Mol Pain. 2015 Oct 24;11:66. doi: 10.1186/s12990-015-0069-3.
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CRHBP polymorphisms predict chronic pain development following motor vehicle collision.促肾上腺皮质激素释放激素结合蛋白多态性可预测机动车碰撞后慢性疼痛的发生。
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基于首次大规模紧急护理的性侵犯后康复纵向队列研究方案:妇女健康研究。

Protocol for the first large-scale emergency care-based longitudinal cohort study of recovery after sexual assault: the Women's Health Study.

机构信息

Psychiatry, Medical University of South Carolina, Charleston, South Carolina, USA.

Department of Anesthesiology, UNC-Chapel Hill, Chapel Hill, North Carolina, USA.

出版信息

BMJ Open. 2019 Nov 21;9(11):e031087. doi: 10.1136/bmjopen-2019-031087.

DOI:10.1136/bmjopen-2019-031087
PMID:31753875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6887008/
Abstract

INTRODUCTION

Worldwide, an estimated 10%-27% of women are sexually assaulted during their lifetime. Despite the enormity of sexual assault as a public health problem, to our knowledge, no large-scale prospective studies of experiences and recovery over time among women presenting for emergency care after sexual assault have been performed.

METHODS AND ANALYSIS

Women ≥18 years of age who present for emergency care within 72 hours of sexual assault to a network of treatment centres across the USA are approached for study participation. Blood DNA and RNA samples and brief questionnaire and medical record data are obtained from women providing initial consent. Full consent is obtained at initial 1 week follow-up to analyse blood sample data and to perform assessments at 1 week, 6 weeks, 6 months and 1 year. These assessments include evaluation of survivor life history, current health and recovery and experiences with treatment providers, law enforcement and the legal system.

ETHICS AND DISSEMINATION

This study is approved by the University of North Carolina at Chapel Hill's Institutional Review Board (IRB) and the IRB of each participating study site. We hope to present the results of this study to the scientific community at conferences and in peer-reviewed journals.

摘要

简介

在全球范围内,估计有 10%-27%的女性在其一生中遭受过性侵犯。尽管性侵犯是一个严重的公共卫生问题,但据我们所知,尚未对在遭受性侵犯后到急诊就诊的女性进行大规模的前瞻性研究,以了解她们的经历和随时间的恢复情况。

方法和分析

美国各地的治疗中心网络在性侵犯后 72 小时内为年龄在 18 岁及以上的女性提供急诊护理,并邀请她们参与研究。从提供初步同意的女性中获取血液 DNA 和 RNA 样本以及简短的问卷调查和医疗记录数据。在最初的 1 周随访时获得完整同意,以分析血液样本数据,并在 1 周、6 周、6 个月和 1 年时进行评估。这些评估包括评估幸存者的生活史、当前健康和恢复情况,以及与治疗提供者、执法部门和法律系统的经历。

伦理和传播

本研究已获得北卡罗来纳大学教堂山分校的机构审查委员会 (IRB) 和每个参与研究地点的 IRB 的批准。我们希望在会议和同行评议期刊上向科学界介绍这项研究的结果。