University of Toronto, 2075 Bayview Ave M1 700, Toronto, ON, M4N 3M5, Canada.
Am J Clin Dermatol. 2020 Apr;21(2):157-162. doi: 10.1007/s40257-019-00482-2.
Being the most popular non-surgical cosmetic procedure, botulinum neurotoxin (BoNT) injections are increasingly of interest to all cosmetic practitioners across the globe. This article serves to update readers on the new botulinum toxins that are currently in development or close to market in the USA and Canada, including daxibotulinumtoxin A, prabotulinumtoxin A, letibotulinumtoxin A, and botulinum toxin E. Despite having relatively similar characteristics and equivalent clinical efficacies, these neurotoxins manifest a multitude of unique potential advantages that will be explored in this review, including but not limited to a longer duration of action, the absence of animal-derived components or human albumin, and a rapid onset with short duration of action.
作为最受欢迎的非手术美容程序,肉毒杆菌神经毒素 (BoNT) 注射越来越受到全球所有美容从业者的关注。本文旨在为读者提供有关目前正在美国和加拿大开发或接近市场的新型肉毒毒素的最新信息,包括 daxibotulinumtoxin A、prabotulinumtoxin A、letibotulinumtoxin A 和 botulinum toxin E。尽管这些神经毒素具有相对相似的特性和等效的临床疗效,但它们表现出许多独特的潜在优势,这将在本综述中进行探讨,包括但不限于作用持续时间更长、无动物源性成分或人血白蛋白、起效迅速且作用持续时间短。