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巴西绿蜂胶和红蜂胶在牙科应用中的循证研究与观点

Evidence-Based Studies and Perspectives of the Use of Brazilian Green and Red Propolis in Dentistry.

作者信息

Carvalho Claudemir de, Fernandes Wesley Henrique Cabral, Mouttinho Thays Barreto Freitas, Souza Daniela Martins de, Marcucci Maria Cristina, D'Alpino Paulo Henrique Perlatti

机构信息

School of Dentistry, Centro Universitário FUNVIC - UniFUNVIC, São Paulo, Brazil.

Laboratory of Natural Products and Chemometrics, Programa de Pós-Graduação Stricto sensu em Farmácia, Universidade Anhanguera de São Paulo (UNIAN-SP), São Paulo, São Paulo, Brazil.

出版信息

Eur J Dent. 2019 Jul;13(3):459-465. doi: 10.1055/s-0039-1700598. Epub 2019 Dec 3.

DOI:10.1055/s-0039-1700598
PMID:31795009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6890504/
Abstract

This review analyzes the evidence and perspectives of dental use of the green and red propolis produced in Brazil by L. Multiple applications of propolis were found considering its antibacterial, antifungal, anti-inflammatory, immunomodulatory, antiviral, and healing properties. Its therapeutic effects are mainly due to the presence of alcohols, aldehydes, aliphatic acids, aliphatic esters, amino acids, aromatic acids, aromatic esters, flavonoids, hydrocarbyl esters, ethers, fatty acids, ketones, terpenes, steroids, and sugars. Propolis has been mainly used in dentistry in the composition of dentifrices and mouthwashes. Studies have also demonstrated promising use against dentin hypersensitivity, root canal treatment, and other microorganisms. Overall review of the literature presented here demonstrated that both Brazilian green and red propolis are effective for the problems of multiple etiologies that affect the oral cavity in different dental specialties.

摘要

本综述分析了巴西由L.生产的绿色和红色蜂胶在牙科应用方面的证据和观点。考虑到蜂胶的抗菌、抗真菌、抗炎、免疫调节、抗病毒和愈合特性,发现了其多种应用。其治疗效果主要归因于醇类、醛类、脂肪酸、脂肪族酯、氨基酸、芳香酸、芳香族酯、黄酮类、烃基酯、醚类、脂肪酸、酮类、萜类、甾体类和糖类的存在。蜂胶主要用于牙科领域,作为牙膏和漱口水的成分。研究还表明,蜂胶在治疗牙本质过敏、根管治疗及其他微生物方面有潜在用途。此处对文献的全面综述表明,巴西绿色和红色蜂胶对不同牙科专业中影响口腔的多种病因问题均有效。

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本文引用的文献

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Influence of a propolis-based irrigant solution on gap formation and bond strength of posts bonded to root canal dentin using different resin cements.蜂胶基冲洗液对不同树脂水门汀黏结到根管牙本质的桩核间隙形成和黏结强度的影响。
Dent Mater J. 2020 Jun 5;39(3):490-499. doi: 10.4012/dmj.2019-111. Epub 2020 Feb 29.
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Brazilian red propolis reduces orange-complex periodontopathogens growing in multispecies biofilms.巴西红蜂胶可减少多物种生物膜中生长的橙色复合体牙周致病菌。
Biofouling. 2019 Mar;35(3):308-319. doi: 10.1080/08927014.2019.1598976. Epub 2019 Apr 24.
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Applications of Propolis in Dentistry: A Review.蜂胶在牙科中的应用:综述
Ethiop J Health Sci. 2018 Jul;28(4):505-512. doi: 10.4314/ejhs.v28i4.16.
4
Brazilian red propolis: Chemical composition and antibacterial activity determined using bioguided fractionation.巴西红蜂胶:采用生物导向分离法测定的化学成分和抗菌活性。
Microbiol Res. 2018 Sep;214:74-82. doi: 10.1016/j.micres.2018.05.003. Epub 2018 May 4.
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BMC Complement Altern Med. 2018 Jul 18;18(1):219. doi: 10.1186/s12906-018-2281-y.
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Intratubular decontamination ability and physicochemical properties of calcium hydroxide pastes.氢氧化钙糊剂的根管内去污能力和理化性能。
Clin Oral Investig. 2019 Mar;23(3):1253-1262. doi: 10.1007/s00784-018-2549-0. Epub 2018 Jul 7.
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Efficacy of red propolis hydro-alcoholic extract in controlling Streptococcus mutans biofilm build-up and dental enamel demineralization.红蜂胶水醇提取物控制变形链球菌生物膜形成和牙釉质脱矿的功效。
Arch Oral Biol. 2018 Sep;93:56-65. doi: 10.1016/j.archoralbio.2018.05.017. Epub 2018 May 23.
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Brazilian Green Propolis Prevents Cognitive Decline into Mild Cognitive Impairment in Elderly People Living at High Altitude.巴西绿蜂胶可预防高海拔地区老年人认知能力下降至轻度认知障碍。
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Anticancer activity of the supercritical extract of Brazilian green propolis and its active component, artepillin C: Bioinformatics and experimental analyses of its mechanisms of action.巴西绿蜂胶超临界提取物及其活性成分 artepillin C 的抗癌活性:作用机制的生物信息学和实验分析。
Int J Oncol. 2018 Mar;52(3):925-932. doi: 10.3892/ijo.2018.4249. Epub 2018 Jan 22.
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Brazilian Green Propolis Extract Synergizes with Protoporphyrin IX-mediated Photodynamic Therapy via Enhancement of Intracellular Accumulation of Protoporphyrin IX and Attenuation of NF-κB and COX-2.巴西绿蜂胶提取物通过增强原卟啉IX的细胞内积累以及减弱核因子κB和环氧化酶-2,与原卟啉IX介导的光动力疗法协同作用。
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