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深入探讨:肥厚性瘢痕与烧伤的激光重塑综述

Beneath the Surface: A Review of Laser Remodeling of Hypertrophic Scars and Burns.

作者信息

Kuehlmann Britta, Stern-Buchbinder Zachary, Wan Derrick C, Friedstat Jonathan S, Gurtner Geoffrey C

机构信息

Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, California.

Center for Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Regensburg and Caritas Hospital St. Josef, Regensburg, Germany.

出版信息

Adv Wound Care (New Rochelle). 2019 Apr 1;8(4):168-176. doi: 10.1089/wound.2018.0857. Epub 2019 Apr 3.

DOI:10.1089/wound.2018.0857
PMID:31832273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6906753/
Abstract

Hypertrophic scars, keloids, and burn injuries of the skin have a significant impact on patients' lives and impact the health care system tremendously. Treating skin wounds and lesions can be challenging, with a variety of choices available for treatment. Scar and burn managements range from invasive, surgical options such as scar excision to less invasive, nonsurgical alternatives such as laser therapy or topical drug application. Laser treatment has become increasingly popular, with a growing body of research supporting its use for scars and burns. Numerous methods are available for the treatment of these skin diseases, including different nonsurgical laser therapies. To date, the optimal treatment method for scars, keloids, and burn injuries of the skin has not yet been established, although it is an area of increasing clinical concern. This review provides an updated summary of the treatment of scars and burn wounds of the skin using different laser treatments, including the most recent technologies. It addresses their indications, mechanisms of action, differences, efficacies, and complications.

摘要

肥厚性瘢痕、瘢痕疙瘩和皮肤烧伤对患者的生活有重大影响,并给医疗保健系统带来巨大负担。治疗皮肤伤口和损伤具有挑战性,治疗方法多种多样。瘢痕和烧伤的管理范围从侵入性的手术选择(如瘢痕切除)到侵入性较小的非手术选择(如激光治疗或局部用药)。激光治疗越来越受欢迎,越来越多的研究支持其用于瘢痕和烧伤的治疗。治疗这些皮肤疾病有多种方法,包括不同的非手术激光疗法。迄今为止,尽管这是一个临床关注度日益增加的领域,但皮肤瘢痕、瘢痕疙瘩和烧伤的最佳治疗方法尚未确立。本综述提供了使用不同激光治疗(包括最新技术)治疗皮肤瘢痕和烧伤创面的最新总结。它阐述了这些治疗方法的适应症、作用机制、差异、疗效和并发症。

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本文引用的文献

1
Treatment of post-burn and post-traumatic atrophic scars with fractional CO laser: experience at a tertiary care centre.剥脱性二氧化碳激光治疗烧伤后及创伤后萎缩性瘢痕:三级护理中心的经验
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Treatment Strategies for Hypopigmentation in the Context of Burn Hypertrophic Scars.烧伤增生性瘢痕所致色素减退的治疗策略
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Clinical efficacy of utilizing Ultrapulse CO combined with fractional CO laser for the treatment of hypertrophic scars in Asians-A prospective clinical evaluation.超脉冲CO₂联合非剥脱性CO₂激光治疗亚洲人增生性瘢痕的临床疗效——一项前瞻性临床评估
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Laser in the management of burn scars.激光在烧伤瘢痕治疗中的应用
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Effects of early combinatorial treatment of autologous split-thickness skin grafts in red duroc pig model using pulsed dye laser and fractional CO laser.在红色杜洛克猪模型中使用脉冲染料激光和剥脱性二氧化碳激光对自体中厚皮片进行早期联合治疗的效果
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Update of Ablative Fractionated Lasers to Enhance Cutaneous Topical Drug Delivery.用于增强皮肤局部药物递送的剥脱性分次激光的更新
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Current Therapeutic Approach to Hypertrophic Scars.肥厚性瘢痕的当前治疗方法。
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