文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

拉丁美洲寨卡病毒的出现对地方性登革热传播的影响。

Impacts of Zika emergence in Latin America on endemic dengue transmission.

机构信息

Department of Biology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, 32610, USA.

Odum School of Ecology, University of Georgia, Athens, GA, 30602, USA.

出版信息

Nat Commun. 2019 Dec 16;10(1):5730. doi: 10.1038/s41467-019-13628-x.

DOI:10.1038/s41467-019-13628-x
PMID:31844054
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6915707/
Abstract

In 2015 and 2016, Zika virus (ZIKV) swept through dengue virus (DENV) endemic areas of Latin America. These viruses are of the same family, share a vector and may interact competitively or synergistically through human immune responses. We examine dengue incidence from Brazil and Colombia before, during, and after the Zika epidemic. We find evidence that dengue incidence was atypically low in 2017 in both countries. We investigate whether subnational Zika incidence is associated with changes in dengue incidence and find mixed results. Using simulations with multiple assumptions of interactions between DENV and ZIKV, we find cross-protection suppresses incidence of dengue following Zika outbreaks and low periods of dengue incidence are followed by resurgence. Our simulations suggest correlations in DENV and ZIKV reproduction numbers could complicate associations between ZIKV incidence and post-ZIKV DENV incidence and that periods of low dengue incidence are followed by large increases in dengue incidence.

摘要

2015 年和 2016 年，寨卡病毒（ZIKV）在拉丁美洲登革热病毒（DENV）流行地区肆虐。这两种病毒同属一个家族，共享一个传播媒介，可能通过人类免疫反应发生竞争或协同作用。我们研究了寨卡疫情之前、期间和之后巴西和哥伦比亚的登革热发病率。我们发现有证据表明，2017 年这两个国家的登革热发病率都异常低。我们调查了次国家级寨卡病毒发病率与登革热发病率变化之间的关系，结果喜忧参半。我们使用了多种关于 DENV 和 ZIKV 相互作用的假设进行模拟，发现交叉保护抑制了寨卡病毒爆发后的登革热发病率，而登革热发病率较低的时期之后会出现疫情反弹。我们的模拟表明，DENV 和 ZIKV 繁殖数之间的相关性可能会使寨卡病毒发病率与寨卡病毒后 DENV 发病率之间的关联复杂化，而且登革热发病率较低的时期之后会出现登革热发病率的大幅增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b414/6915707/f6480a1b4ec7/41467_2019_13628_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b414/6915707/2800a47bdeb0/41467_2019_13628_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b414/6915707/f6480a1b4ec7/41467_2019_13628_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b414/6915707/2800a47bdeb0/41467_2019_13628_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b414/6915707/f6480a1b4ec7/41467_2019_13628_Fig4_HTML.jpg

相似文献

[1]
Impacts of Zika emergence in Latin America on endemic dengue transmission.

Nat Commun. 2019-12-16

[2]
Human T cell responses to Dengue and Zika virus infection compared to Dengue/Zika coinfection.

Immun Inflamm Dis. 2017-12-28

[3]
Lying in wait: the resurgence of dengue virus after the Zika epidemic in Brazil.

Nat Commun. 2021-5-11

[4]
Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice.

Cell Host Microbe. 2018-11-14

[5]
ELISPOT-Based "Multi-Color FluoroSpot" to Study Type-Specific and Cross-Reactive Responses in Memory B Cells after Dengue and Zika Virus Infections.

Methods Mol Biol. 2018

[6]
Human antibody response to Zika targets type-specific quaternary structure epitopes.

JCI Insight. 2019-4-18

[7]
Modulation of Dengue/Zika Virus Pathogenicity by Antibody-Dependent Enhancement and Strategies to Protect Against Enhancement in Zika Virus Infection.

Front Immunol. 2018-4-23

[8]
Comparison of Anti-Dengue and Anti-Zika IgG on a Plasmonic Gold Platform with Neutralization Testing.

Am J Trop Med Hyg. 2021-3-29

[9]
An epidemiological survey of the current status of Zika and the immune interaction between dengue and Zika infection in Southern Taiwan.

Int J Infect Dis. 2020-1-23

[10]
Sustained Specific and Cross-Reactive T Cell Responses to Zika and Dengue Virus NS3 in West Africa.

J Virol. 2018-3-14

引用本文的文献

[1]
Estimating transmissibility of Zika virus in Colombia in the presence of surveillance bias.

Nat Commun. 2025-5-8

[2]
Zika virus vaccines and monoclonal antibodies: a priority agenda for research and development.

Lancet Infect Dis. 2025-7

[3]
Histone deacetylases synergistically regulate juvenile hormone signaling in the yellow fever mosquito, Aedes aegypti.

Insect Biochem Mol Biol. 2025-2

[4]
Sentinel Enhanced Dengue Surveillance System - Puerto Rico, 2012-2022.

MMWR Surveill Summ. 2024-5-30

[5]
Identification and characterization of a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope.

Proc Natl Acad Sci U S A. 2024-5-21

[6]
Resurgence of Dengue Virus Serotype 3 in Minas Gerais, Brazil: A Case Report.

Pathogens. 2024-2-24

[7]
Shifting patterns of dengue three years after Zika virus emergence in Brazil.

Nat Commun. 2024-1-20

[8]
Effects of boosting and waning in highly exposed populations on dengue epidemic dynamics.

Sci Transl Med. 2023-11-15

[9]
Convergent trends and spatiotemporal patterns of Aedes-borne arboviruses in Mexico and Central America.

PLoS Negl Trop Dis. 2023-9

[10]
Primary infection with Zika virus provides one-way heterologous protection against Spondweni virus infection in rhesus macaques.

Sci Adv. 2023-6-30

本文引用的文献

[1]
Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region.

Science. 2019-2-8

[2]
Arbovirus coinfection and co-transmission: A neglected public health concern?

PLoS Biol. 2019-1-22

[3]
Seroprevalence, risk factor, and spatial analyses of Zika virus infection after the 2016 epidemic in Managua, Nicaragua.

Proc Natl Acad Sci U S A. 2018-8-27

[4]
Coinfection with Zika Virus (ZIKV) and Dengue Virus Results in Preferential ZIKV Transmission by Vector Bite to Vertebrate Host.

J Infect Dis. 2018-7-13

[5]
Longitudinal Analysis of Antibody Cross-neutralization Following Zika Virus and Dengue Virus Infection in Asia and the Americas.

J Infect Dis. 2018-7-13

[6]
Does immunity after Zika virus infection cross-protect against dengue?

Lancet Glob Health. 2018-2

[7]
Human T cell responses to Dengue and Zika virus infection compared to Dengue/Zika coinfection.

Immun Inflamm Dis. 2017-12-28

[8]
High Zika Virus Seroprevalence in Salvador, Northeastern Brazil Limits the Potential for Further Outbreaks.

mBio. 2017-11-14

[9]
Establishment and cryptic transmission of Zika virus in Brazil and the Americas.

Nature. 2017-6-15

[10]
Impact of simultaneous exposure to arboviruses on infection and transmission by Aedes aegypti mosquitoes.

Nat Commun. 2017-5-19

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索