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抗结核药物不良反应与三级转诊医院患者生活质量的关系。

Association of adverse drug reaction to anti-tuberculosis medication with quality of life in patients in a tertiary referral hospital.

机构信息

Universidade Federal de Minas Gerais, Faculdade de Medicina, Programa de Pós-Graduação em Ciências Aplicadas à Saúde do Adulto, Belo Horizonte, MG, Brasil.

Fundação Hospitalar do Estado de Minas Gerais, Hospital Júlia Kubitschek. Belo Horizonte, MG, Brasil.

出版信息

Rev Soc Bras Med Trop. 2019 Dec 20;53:e20190207. doi: 10.1590/0037-8682-0207-2019. eCollection 2019.

DOI:10.1590/0037-8682-0207-2019
PMID:31859946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7083343/
Abstract

INTRODUCTION

Adverse drug reactions can develop when using anti-tuberculosis medication, and the effects of the drugs can also significantly hinder the treatment of patients.

METHODS

A cross-sectional survey was conducted in 73 patients using two standardized questionnaires and the World Health Organization Quality of Life-Bref.

RESULTS

All patients reported the presence of adverse drug reactions, 71.6% of which are minor and 28.3% both major and minor. The global quality of life analysis showed that patients with tuberculosis have a good average (67.3%).

CONCLUSIONS

There is an association between quality of life and adverse drug reaction, educational level, and vulnerability.

摘要

简介

使用抗结核药物时可能会产生药物不良反应,而且药物的作用也会严重阻碍患者的治疗。

方法

采用横断面调查,对 73 名患者使用两份标准化问卷和世界卫生组织生活质量简表进行调查。

结果

所有患者均报告存在药物不良反应,其中 71.6%为轻度,28.3%为中重度。整体生活质量分析表明,肺结核患者的平均生活质量较好(67.3%)。

结论

生活质量与药物不良反应、教育水平和脆弱性有关。

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